HVS - The Heart Valve Society 2016 Scientific Meeting

2nd Annual Meeting, March 17-19, 2016, Marriott Marquis, NYC

2016 Preliminary Program

Preliminary Program		Moderated Poster Competition		Posters

THURSDAY, MARCH 17TH

8.30 - 10.00

Opening Plenary Session: Next Decade in Valve Disease

Moderators:

Maurice E. Sarano, MD, President
Gilles D. Dreyfus, MD, President-Elect
Michael A. Borger, MD, Past President

8.30 - 8.35

Welcome
Maurice E. Sarano, MD

8.35 - 8.49

The Epidemics of Valve Disease Will Rise
Bernard Prendergast, MD

8.49 - 9.03

Genetics of Valve Disease Will Be Everything
Robert A. Levine, MD

9.03 - 9.17

Interventional Treatment Will Treat Every Valve Disease
Alec Vahanian, MD

9.17 - 9.31

Tissue Biomechanics Will Tell Us Everything
Jane Grande-Allen, MD

9.31 - 9.45

Robotic Valve Surgery Will Be The Standard Therapy for Degenerative Disease
Rakesh Suri, MD

9.45 - 9.50

Announcement of Borer Travel Awards
Maurice E. Sarano, MD & Jeffery S. Borer, MD

9.45 - 10.00

Presidential Address
Maurice E. Sarano, MD

10.00 - 10.30

Coffee Break & Poster Viewing

10.30 - 12.00

Concurrent Session I: Aortic Stenosis

Moderators:

Vinod Thourani, MD
Susheel Kodali, MD

10.30 - 10.42

New natural history and new classification in AS
Luc Pierard, MD

10.42 - 10.54

The new markers of severity of AS (BNP, calcifications)
Philippe Pibarot, DVM, PhD

10.54 - 11.06

Surgical approaches to AVR: is minimally invasive safer?
Vinod Thourani, MD

11.06 - 11.18

Sutureless prostheses: The way of the future…
Michael Borger, MD

11.18 - 11.30

TAVR 2016: How will we tackle periposthetic AR
Susheel Kodali, MD

11.30 - 12.00

Discussion

Concurrent Session II: Aortic Valve Repair: Let's Do It!

Moderators:

Emmanuel Lansac, MD
Hans-Joachim Schaefers, MD

10.30 – 10.45

Echocardiographic Predictors of Reparability
Alain Berrebi, MD

10.42 – 10:54

What do I need to know from echo to repair the aortic valve
Gebrine El-Khoury, MD

10.54 – 11.06

Valve-Sparing Root Replacement: Why and How to Do It?
Laurent de Kerchove, MD, PhD

11.06 – 11.18

Isolated Aortic Valve Repair: Why and How to Do It?
Hans-Joachim Schaefers, MD

11.18 – 11.30

Rationales to Standardize Aortic Valve Repair
Emmanuel Lansac, MD

11.30 – 12.00

Discussion

Concurrent Session III: Biomarkers in Valve Disease

Moderators:

Marie-Annick Clavel, MD
Mac Dweck, MD

10.30 - 10.45

Natriuretic Peptide in Organic Mitral Regurgitation
Rodolfo Pizarro, MD

10.45 - 11.00

Natriuretic Peptide in Aortic Stenosis
Jutta Bergler-Klein, MD

11.00 - 11.15

Novel Biomarkers for Aortic Stenosis
Brian Lindman, MD

11.15 - 11.30

MicroRNA as Biomarkers in Aortic Stenosis
Magnus Back, MD

11.30 - 12.00

Discussion

Concurrent Session IV: Experience and Innovation in Tissue Engineered Heart Valves Keynote & Abstracts

Moderator:

John Mayer, MD

10:30 - 10:45

Keynote
John Mayer, MD

10.45 - 10.55

A1. In-Situ Heart Valve Tissue Engineering - is On-the-fly Preseeding with Bone Marrow-derived Cells Required?
Anthal I.P.M. Smits, Virginia Ballotta, Anita Driessen-Mol, Frank P.T. Baaijens, Carlijn V.C. Bouten.
Eindhoven University of Technology, Eindhoven, Netherlands.

10.55 - 11.05

A2. Performance of Size-Reduced Bicuspidalized Decellularized Pulmonary Valve Conduits in Growing Sheep Model
Karolina Theodoridis, Igor Tudorache, Andres Hilfiker, Tanja Mayer, Samir Sarikouch, Christoph Bara, Alexandru Calistru, Thomas Breymann, Alexander Horke, Axel Haverich, Serghei Cebotari.
Hannover Medical School, Hannover, Germany.

11.05 - 11.15

A3. How Close Are We to Fully Engineering a Living Heart Valve? A Tale of Scaffolds, Stem Cells, Bioreactors and Sheep
Marius M. Harpa¹, Ionela Movileanu¹, Allison Kennamer², Nicholas Rierson², Ovidiu Cotoi¹, Horatiu Suciu¹, Victor Raicea¹, Terezia Preda¹, Dan Nistor¹, Klara Branzaniuc¹, Radu Deac¹, Simona Gurzu¹, Lucian Harceaga¹, Peter Olah¹, Carmen Sircuta¹, Agneta Simionescu², Michael Dandel¹, Dan Simionescu².
¹University of Medicine and Pharmacy, Targu Mures, Romania, ²Clemson University, Clemson, SC, USA.

11.15 - 11.25

A4. Echocardiographic Leaflet Performance of Stentless Extracellular Matrix Tricuspid Tube graft in a Porcine Model
Diana M. Ropcke, Christine Ilkjaer, Soren N. Skov, Marcell J. Tjornild, Anders V. Sorensen, Henrik Jensen, Sten L. Nielsen.
Aarhus University Hospital, Aarhus C, Denmark.

11.25 - 11.35

A5. Bioresorbable Reinforcement of Neopulmonary Trunk Avoids Sovrapulmonary Stenosis in Arterial Switch Operation: Biomechanics, Growth and Remodelling
Mario Fittipaldi¹, Cristiano Spadaccio², Antonio Nenna³, Massimiliano Fraldi⁴, Francesco Nappi⁵.
¹Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom, ²Golden Jubilee National Hospital, Glasgow, United Kingdom, ³University Campus Bio-Medico, Rome, Italy, ⁴University Federico II of Naplesples, Naples, Italy, ⁵Centre Cardiologique du Nord, Paris, France.

11.35 - 11.45

A6. Bioabsorbable Vascular Graft - the First Step Towards Development of the Next Generation Heart Valves
Leo Bockeria¹, Alex Kim¹, Konstantin Shatalov¹, Vladimir Makarenko¹, Oleg Svanidze².
¹Bakoulev Center for Cardiovascular Surgery, Moscow, Russian Federation, ²Xeltis AG, Zurich, Switzerland.

11.45 - 11.55

A7. A Nitinol Mesh Scaffold for Heart Valve Engineering
Seyedhamed Alavi, Marc S. Baliarda, Lorenzo Valdevit, Arash Kheradvar.
University of California, Irvine, Irvine, CA, USA.

Concurrent Session V: Heart Valve Outcomes I Keynote & Abstracts

Moderator(s):

Jeffery Borer, MD

10:30 - 10:45

Keynote
Jeffery Borer, MD

10.45 - 10.55

A8. Fresh Decellularized Pulmonary Valve Allografts For Rvot Reconstruction During The Ross Operation - Clinical Outcomes At 10 Years
Francisco D. Costa¹, Eduardo Balbi, Filho², Rafael Torres², Daniele Colatusso¹, Claudinei Colatusso¹, Allysson Calixto², Marise Costa¹.
¹Santa Casa de Curitiba PUCPR, Curitiba, Brazil, ²Instituto de Neurologia e Cardiologia de Curitiba, Curitiba, Brazil.

10.55 - 11.05

A9. Human Factors During Mitral Valve Replacement Surgery Are Associated With Adverse Events
Jock N. McCullough, MD¹, Alexander Iribarne, MD¹, David C. Charlesworth, MD², Robert A. Cough, MD³, Joseph P. DeSimone, MD¹, Carmine Frumiento, MD⁴, Robert S. Kramer, MD⁵, Bruce J. Leavitt, MD⁶, Charles A. Marrin, MD¹, Jeremy R. Morton, MD⁵, Joseph D. Schmoker, MD⁶, Benjamin M. Westbrook, MD², Anthony W. DiScipio, MD¹.
¹Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA, ²Catholic Medical Center, Manchester, NH, USA, ³Eastern Maine Medical Center, Bangor, ME, USA, ⁴Central Maine Medical Center, Lewiston, ME, USA, ⁵Maine Medical Center, Portland, ME, USA, ⁶University of Vermont Medical Center, Burlington, VT, USA.

11.05 - 11.15

A10. Familial Clustering of Mitral Regurgitation in the Community
Francesca N. Delling¹, Shuo Li, MS², Qiong Yang, PhD³, Vanessa Xanthakis, PhD², Birgitta Lehman, RDCS⁴, Ewa Osypiuk, MD⁴, Plamen Stantchev, MD⁴, Emelia J. Benjamin, MD², Ramachandran S. Vasan, MD².
¹Beth Israel Deaconess Medical Center, Boston, MA, USA, ²Boston University School of Medicine, Boston, MA, USA, ³Boston University School of Public Health, Boston, MA, USA, ⁴Framingham Heart Study, Framingham, MA, USA.

11.15 - 11.25

A11. Outcome After Mechanical Aortic Valve Replacement In Adult Patients Under 55 Years: A Systematic Review, Meta-analysis And Microsimulation
Nelleke M. Korteland, Jonathan R.G. Etnel, Bardia Arabkhani, Arezo Mohamad, M. Mostafa Mokhles, Ad J.J.C. Bogers, Johanna J.M. Takkenberg.
Erasmus MC, Rotterdam, Netherlands.

11.25 - 11.35

A12. Computed tomography and Echo evaluation of Left Ventricular Remodeling in Patients with Severe Degenerative Mitral Regurgitation
Zhenhua Li¹, Rakesh M. Suri², Thomas A. Foley³, Eric E. Williamson³, Maurice Enriquez-Sarano¹, Hector I. Michelena¹.
¹Division of Cardiovascular Diseases and Internal Medicine,Mayo Clinic, Rochester, MN, USA, ²Department of Thoracic and Cardiovascular Surgery,Cleveland Clinic, Cleveland, OH, USA, ³Department of Radiology,Mayo Clinic, Rochester, MN, USA.

11.35 - 11.45

A13. Restrictive Indications for the Ross Procedure Improve Long Term Outcomes
Zohair Y. Alhalees, Valeria Pergola, Giovanni Di Salvo, Maie Alshahid, Bahaa Fadel, Mohammed Alamri, Ziad Issa, Mamdouh Alahmadi, Saud Aloufi.
KFSHRC, Riyadh, Saudi Arabia.

11.45 - 11.55

A14. Aortic Valve Replacement - Paradox in Patients With Paradoxical Low Flow
Anthony Poulin, Maxime Berthelot-Richer, Lionel Tastet, Louis Simard, Dimitri Kalavrouziotis, Philippe Pibarot, Marie-Annick Clavel.
Quebec Heart and Lung Institute, Québec, QC, Canada.

12:00 - 13.30

Industry Lunch Symposium

13.30 - 15.00

Concurrent Session I: Great Debates

13.30 - 14.15

Debate I: Functional MR Is Best Treated Percutaneously

Moderators:

Paul Sorajja, MD
Michael Borger, MD

13.30 - 13.45

PRO: My favorite is the Mitral Clip
Saibal Kar, MD

13.45 - 14.00

CON: Surgical Repair Is The Standard Of Care
Steven Bolling, MD

14.00 - 14.15

Reconciliation with moderators

14.15 - 15.00

Debate II: TAVR In Low Risk Patients

Moderators:

Gregory Fontana, MD
Nicolo Piazza, MD

14.15 - 14.30

PRO Nicolo Piazza, MD

14.30 - 14.45

CON Craig R. Smith, MD

14.45 - 15.00

Reconciliation with moderators

Concurrent Session II: Bicuspid Aortic Valve: Clinical & Basic Science

Moderators:

Hector Michelena, MD
Alex Barker, MD
Patrick Mathieu, MD
Rakesh Suri, MD

13.30 - 13.42

New genetic developments: Common and rare genetic variants in BAV
Siddharth Prakash, MD

13.42 - 13.54

The wonders of 4D-flow MR: Ready for clinical use?
Alex Barker, PhD

13.54 - 14.06

Do valvulo-aortic phenotypes predict dissection risk?
Evaldas Girdauskas, MD, PhD

14.06 - 14.18

Embryology of BAV: is there a link with long-term morbidity?
Philippe Sucosky, PhD

14.18 - 14.30

Is BAV repair a durable alternative? For who?
Laurent De Kerchove, MD

14.30 - 15.00

Discussion

Concurrent Session III: Tissue Engineering

Moderators:

Carlijn Bouten, MD
Ulrich Stock, MD

13.30 - 13.42

Tissue Engineering of Heart Valves - From In Vitro to In Vivo
Ulrich Stock, MD

13.42 - 13.54

6-Month Aortic Valve Implantation of an Off-The-Shelf Tissue-Engineered Valve in Sheep
Zeeshan Syedain, MD

13.54 - 14.06

Transcatheter off-the-shelf tissue engineered heart valves with self-repair capacity: long term results from a translational ovine model
Max Emmert, MD

14.06 - 14.18

Long-Term In-Vivo Follow Up of Biomaterial-Based In-Situ Heart Valve Tissue Engineering
Carlijn Bouten, MD

14.18 - 14.30

New Approaches in Heart Valve Pathobiology: Implications for Tissue Engineering
Elena Aikawa, MD

14.30 - 15.00

Discussion

Concurrent Session IV: Experimental and Computational Analyses of Valve Disease and Treatment Keynote & Abstracts

Moderator:

Ajit Yoganathan, Ph.D.

13.30 - 13.45

Keynote
Ajit Yoganathan, Ph.D.

13.45 - 13.55

A15. A Study of Tunable Biaxial Strain Fields on Aortic Heart Valve Tissues
Ying Lei, Zannatul Ferdous.
The University of Tennessee, Knoxville, TN, USA.

13.55 - 14.05

A16. Infectious Agents related with Collagen Degradation and Inflammation in Myxomatous Mitral Valve Degeneration
Marcos G. Tiveron, Sr., Pablo M. A. Pomerantzeff, Sr., Maria L. Higuchi, Marcia Reis, Jaqueline Pereira, Joyce Kawakami, Renata Ikegami, Carlos M. Brandao, Sr., Fabio B. Jatene, Sr..
Heart Institute, Sao Paulo, Brazil.

14.05 - 14.15

A17. Patient-Specific Computational Modeling of Mitral Valve Repair Techniques
Thuy Pham¹, Fanwei Kong¹, Caitlin Martin¹, Qian Wang¹, Charles Primiano², Raymond McKay², John Elefteriades³, Wei Sun¹.
¹Georgia Institute of Technology, Atlanta, GA, USA, ²Hartford Hospital, Hartford, CT, USA, ³Yale University, New Haven, CT, USA.

14.15 - 14.25

A18. Computational Simulation of In Vivo Pulmonary Autograft Early After the Ross Procedure: Wall Stress Analysis
Yue Xuan, PhD¹, Hesam S. Moghaddam, PhD¹, Ismail El-Hamamsy, MD PhD², Francois-Pierre Mongeon, MD², Richard L. Leask, PhD³, Alexander Emmott³, Elaine E. Tseng, MD¹, Liang Ge, PhD¹.
¹UCSF Medical Center and San Francisco VA, San Francisco, CA, USA, ²Montreal Heart Institute and Université de Montréal, Montreal, QC, Canada, ³McGill University, Montreal, QC, Canada.

14.25 - 14.35

A19. Remodeling of Tissue Engineered Heart Valves During a One Year Follow-up Period in Sheep - A Computational Experimental Analysis
Sandra Loerakker¹, Bart Sanders¹, Boris Schmitt², Petra E. Dijkman³, Hendrik Spriestersbach², Anita Driessen-Mol¹, Emanuela S. Fioretta¹, Marco Bartosch², Laura Frese³, Simon P. Hoerstrup³, Felix Berger², Frank P.T. Baaijens¹.
¹Eindhoven University of Technology, Eindhoven, Netherlands, ²Deutsches Herzzentrum Berlin, Berlin, Germany, ³University and University Hospital Zurich, Zurich, Switzerland.

14.35 - 14.45

A20. A New Fluid-Structure Interaction Model for Bicuspid Aortic Valves
Karin Lavon¹, Rotem Halevi¹, Gil Marom², Sagit Ben Zekry³, Rami Haj-Ali¹, Hans Joachim Schäfers⁴, Ehud Raanani⁵.
¹School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel, ²Biomedical Engineering Department, Stony Brook University, ¹¹⁷⁹⁴, NY, USA, ³Echocardiography Laboratory, Chaim Sheba Medical Center, Tel Hashomer, Israel, ⁴Department of Thoracic and Cardiovascular Surgery, University Hospitals of Saarland, Homburg, Germany, ⁵Department of Cardio- thoracic Surgery, Chaim Sheba Medical Center, Tel Hashomer, Israel.

14.45 - 14.55

A21. Initial Impact of Bicuspid Aortic Valve Morphotype on Ascending Aorta Hemodynamics: an In Vitro Study
Andrew McNally¹, Philippe Sucosky².
¹University of Notre Dame, South Bend, IN, USA, ²Wright State University, Dayton, OH, USA.

Concurrent Session V: Heart Valve Repair Keynote & Abstracts

Moderator:

Ottavio Alfieri, MD

13:30 - 13:45

Keynote
Ottavio Alfieri, MD

13.45 - 13.55

A22. Ten Year Single Center Experience with Robotic Assisted Mitral Valve Repair
Alfredo Trento, MD, Danny Ramzy, MD, PhD, Michele De Robertis, RN, James Mirocha, MS, Wen Cheng, MD, Lawrence Czer, MD.
Cedars-Sinai Medical Center, Los Angeles, CA, USA.

13.55 - 14.05

A23. Remodeling Associated With Aortic Ring Annuloplasty: Long Term Results of a Physiological Approach to Valve Sparing
Emmanuel LANSAC¹, Isabelle Di Centa², Ghassan Sleilaty¹, Stéphanie Lejeune¹, Nizar Khelil¹, Alain Berrebi¹, Christelle Diakov¹, Leila Mankoubi¹, Marie Christine Malergue¹, Milena Noghin¹, Konstantinos Zannis¹, Suzanna Salvi¹, Patrice Dervanian¹, Mathieu Debauchez¹.
¹Institut Mutualiste Montsouris, PARIS, France, ²Hopital Foch, Suresnes, France.

14.05 - 14.15

A24. Predictors of New-Onset Atrial Fibrillation in Preserved Ejection Fraction Patients Undergoing Isolated Mitral Valve Repairs
J. Trent Magruder, Sarah Collica, Stephen Belmustakov, Todd C. Crawford, Joshua C. Grimm, Duke E. Cameron, William A. Baumgartner, Kaushik Mandal.
Johns Hopkins, Baltimore, MD, USA.

14.15 - 14.25

A25. Combined Mitral and Aortic Valve Reconstruction
Alexander Wick, Diana Aicher, Christian Giebels, Takahashi Kunihara, Hans-Joachim Schäfers.
Saarland University, Homburg, Germany.

14.25 - 14.35

A26. Mitral Stenosis After Mitral Valve Repair For Degenerative Disease May Limit Exercise Capacity
Kiyoshi Doi, Hitoshi Yaku, Satoshi Numata, Sachiko Yamazaki, Keiichi Itatani, Suguru Ohira, Kaichiro Manabe, Kiminori Ikemoto, Tetsuhiro Yamano.
Kyoto Prefectural University of Medicine, Kyoto, Japan.

14.35 - 14.45

A27. Tricuspid Valve Repair: What to Do When a Ring Is Not Enough.
Matteo Pettinari, Philip Bertrand, Herbert Gutermann, Christiaan Van Kerrebroeck, Robert Dion.
Ziekenhuis Oost Limburg, Genk, Belgium.

14.45 - 14.55

A28. Early Echocardiographic Outcomes of Mitral Valve Annuloplasty versus Annuloplasty Combined with a Papillary Muscle Sling for Moderate to Severe Functional Mitral Regurgitation
Christos G. Mihos^1,2, Romain Capoulade¹, Evin Yucel¹, Serguei Melnitchouk¹, Judy Hung¹.
¹Massachusetts General Hospital, Boston, MA, USA, ²Coulmbia University, Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, FL, USA.

15:00 - 15:30

Coffee Break & Poster Viewing

15.30 - 17.00

Concurrent Session I: Rapid Fire: Mitral and Tricuspid Innovation

Moderator:

David Meerkin, MD
Vinod Thourani, MD
Gilles Dreyfus, MD
Alec Vahanian, MD

In-Audience Moderators:

Maurice E. Sarano, MD
Hector Michelena, MD

15.30 - 15.35

Percutaneous annuloplasty of TR
Gino Nicenig, MD

15:35 - 15:40

The 4Tech approach to TR
Paolo Denti, MD

15.40 - 15.45

Off-pump chordal implant
Gino Gerosa, MD

15.45 - 15:50

Epicardial devices approach for functional MR
Jai Ramen, MD

15:50 - 15:55

The Valtech Cardioband implantation
Francesco Maisano, MD

15:55 - 16:00

Mitral Bridge
Valavanur Subramanian, MD

16:00 - 16:05

Adjustable mitral annuloplasty
Carlos Ruiz, MD

16:05 - 16:10

Docking the TMVR
Rebecca Halm

16:10 - 16:20

Edwards CardiAQ transcatheter mitral valve replacement
Issac George, MD

16.20 - 16.25

The Tendyne TMVR
Paul Sorajja, MD

16.30 - 16.35

The Twelve Mitral Prosthesis
Bernard Prendergast, MD

16.30 - 17.00

Discussion

Concurrent Session II: Rheumatic Disease & Global Epidemiology

Moderators:

Vuyisile Nkomo, MD
Liesl Zuhlke, MD
Bernard Prendergast, MD

15.30 - 15.42

Epidemiology of Rheumatic Heart Disease - Lessons from the Global Burden of Disease
David Watkins, MD

15.42 - 15.54

The Clinical Burden of Rheumatic Heart Disease - Insights from the REMEDY Study
Liesl Zuhlke, MD

15.54 - 16.06

Genetic Determinants of Rheumatic Fever and Rheumatic Heart Disease
Andrea Beaton, MD

16.06 - 16.18

Rheumatic Heart Disease in Samoa
Marvin Allen, MD

16.18 - 16.30

Rheumatic Heart Disease Collaboration in Mozambique
Daniel Sidi, MD

16.30 - 17.00

Discussion

Concurrent Session III: Mechanisms & Prevention of Bioprosthetic Degeneration

Moderator:

Robert Levy, MD
Jean-Christian Roussel, MD

15.30 - 15.42

The Pathophysiologic Determinants of How and Why Valve Bioprostheses Fail
Gaetano Thiene, MD

15.42 - 15.54

Bioprosthetic Heart Valve Structural Degradation: Biomechanical Mechanisms, Modeling, Performance
Michael Sacks, Ph.D.

15.54 - 16.06

The Impact of Oxidative Modifications on Non-Calcific Bioprosthetic Heart Valve Failure
Giovanni Ferrari, Ph.D.

16.06 - 16.18

Immunogenic non-human carbohydrate antigen expression in bioprostheses. Potential link to structural deterioration
Vered Padler-Karavani, Ph.D.

16.18 - 16.30

Pathogenesis and Mitigation of Bioprosthetic Structural Degeneration Due to Mineralization
Robert Levy, MD

16.30 - 17.00

Discussion

Concurrent Session IV: 3-D Echo Imaging

Moderators:

Joseph Maalouf, MD
Francesco Faletra, MD
Alain Berrebi, MD

15.30 - 15.42

The Incremental Value of 3D Echocardiography for Valve Analysis of Mitral and Aortic Regurgitation
Alain Berrebi, MD

15.42 - 15.54

Benefits of Imaging the Tricuspid Valve Using 3D Echocardiography
Rebecca Hahn, MD

15.54 - 16.06

The Evolving Role of 3D TEE in Transcatheter Edge-to-Edge Mitral Valve Repair
Joseph Maalouf, MD

16.06 - 16.18

The Role of 3D TEE in Guiding Transcatheter Closure of Mitral Periprosthetic Leaks and Valve-in-valve Implantation
Sunil Mankad, MD

16.18 - 16.30

New Trends in Echo-Guiding Percutaneous Procedures: The X-Ray-3D Echo Fusion Imaging
Francesco Faletra, MD

16.30 - 17.00

Discussion

Concurrent Session V: Endocarditis

Moderators:

Mariana Mirabel, MD
Milind Desai, MD

15.30 - 15.42

Prophylaxis of Infective Endocarditis
Ann Bolger, MD

15.42 - 15.54

Incremental Value of Multimodality Imaging in IE
Milind Desai, MD

15.54 - 16.06

Endocarditis Team
Milind Desai, MD

16.06 - 16.18

CDRIE
Charles Love, MD

16.18 - 16.30

Timing of Valve Surgery in Adults
Jean-Francois Obadia, MD

16.30 - 16.35

Worldwide Challenges in IE
Mariana Mirabel, MD

16.35 - 17.00

Discussion

17:00 - 17.30

Annual Business Meeting

17.30 - 19:00

Welcome Reception & Moderated Poster Competition

FRIDAY, MARCH 18

8.30 - 10.00

Concurrent Session I: Degenerative MR

Moderators:

Francesco Grigioni, MD
David Adams, MD

8.30 - 8.42

Anatomy and Physiopathology Through Different Imaging Modalities
Vuyisile Nkomo, MD

8.42 - 8.54

Natural History Studies and Indications for Surgery
Francesco Grigioni, MD

8.54 - 9.06

Mitral Repair is Always the Preferred Sugical Technique to Treat Degenerative Mitral Regurgitation (or Maybe Not)
David Adams, MD

9.06 - 9.18

Percutaneous Treatment of Degenerative Mitral Regurgitation: Where Do We Stand and Where Should We Go?
Francesco Maisano, MD

9.18 - 9.30

Rational and Potential Benefits of Minimally Invasive Surgery
Didier Loulmet, MD

9.30 - 10.00

Discussion

Concurrent Session II: Managing Complications of Transcatheter Valve Therapies

Moderators:

Jeorg Kemfert, MD
Matthew Verghese, MD

8.30 - 8.40

Valve Embolization
Gurpreet Sandhu, MD

8.40 - 8.50

TAVR Related Mitral Regurgitation
Verghese Matthew, MD

8.50 - 9.00

Aortic Annular Rupture/TAVR Castastrophe
Kevin Greason, MD

9.00 - 9.10

Aortic Dissection
Norman Mangner, MD

9.10 - 9.20

Annular Rupture: How to avoid and how to manage
Axel Unbehaun, MD

9.20 - 9.30

Stroke during TAVR
Jorg Kempfert, MD

9.30 - 10.00

Discussion

Concurrent Session III: Valve Calcification: Clinical & Basic Science

Moderators:

Jordan Miller, MD
David Messika-Zeitoun, MD

8.30 - 8.45

Animal Models of Valve Disease: Great Utility or Ultimate Futility?
Jordan Miller, MD

8.45 - 9.00

Leveraging the Genetics of Valve Calcification at the Dawn of Precision Medicine
Yohan Bosse, MD

9.00 - 9.15

Deriving Prognostic Information from Vlave Calcification: "The Doctor Will CT You Now…."
David Messika-Zeitoun, MD

9.15 - 9.30

New Imaging Modalities in Valve Disease: The Next Wave of Actionable Intelligence
Marc Dweck, MD

9.30 - 10.00

Discussion

Concurrent Session IV: Heart Valve Imaging Keynote & Abstracts

Moderator:

Jim Thomas, MD

8.30 - 8.45

Keynote
Jim Thomas, MD

8.45 - 8.55

A29. Assessment of Myocardial Fibrosis in Aortic Stenosis using Cardiac Magnetic Resonance Imaging
Calvin Chin¹, Russell J. Everett², Jacek Kwiecinski³, Alex Vesey², Emily Yeung², Gavin Esson², William Jenkins², Maria Koo², Saeed Mirsadraee², Audrey White², Alan Japp², Sanjay Prasad⁴, Scott Semple⁵, David Newby², Marc Dweck².
¹Department of Cardiovascular Science,National Heart Center, Singapore, Singapore, ²University of Edinburgh, Edinburgh, United Kingdom, ³First Department of Cardiology, Poznan University of Medical Sciences, Poland, Poland, ⁴Royal Brompton Hospital, London, United Kingdom, ⁵Clinical Research Imaging Centre, Edinburgh, United Kingdom.

8.55 - 9.05

A30. Causes and Mechanisms of Isolated Mitral Regurgitation in the Community: Impact and Outcome
Volha Dziadzko, Marie-Annick Clavel, Maurice Enriquez-Sarano.
Mayo Clinic, Rochester, MN, USA.

9.05 - 9.15

A31. Aortic Valve Stenosis Complicates the Hemodynamic Hypothesis for Regional Bicuspid Aortic Valve Aortopathy Development
Alex J. Barker¹, Pim van Ooij², Emilie Bollache¹, S Chris Malaisrie¹, Patrick M. McCarthy¹, Jeremy Collins¹, James Carr¹, Paul W. M. Fedak³, Michael Markl¹.
¹Northwestern University, Chicago, IL, USA, ²Amsterdam Medical Center, Amsterdam, Netherlands, ³University of Calgary, Calgary, AB, Canada.

9.15 - 9.25

A32. Low Ejection Fraction, Low-Flow, Low-Gradient Aortic Stenosis: Dobutamine Stress Echocardiographic Criteria to Assess Stenosis Severity
Eden Touboul¹, Abdellaziz Dahou¹, Ian Burwash², Maurice Enriquez-Sarano³, Jutta Bergler-Klein⁴, Stefan Orwat⁵, Helmut Baumgartner⁵, Gerald Mundigler⁴, Eric Larose¹, Philippe Pibarot¹, Marie-Annick Clavel¹.
¹IUCPQ, Quebec, QC, Canada, ²Ottawa Heart Institute, Ottawa, ON, Canada, ³Mayo CLinic, Rochester, MN, USA, ⁴Vienna General Hospital, Vienna, Austria, ⁵Muenster general hospital, Muenster, Germany.

9.25 - 9.35

A33. The En-Face Quantitative Analysis of Valvular Calcification; Novel Physiological Insights into Aortic Stenosis using 4-dimensional Computed Tomography.
William S. Jenkins¹, Louis Simard², Jérome Hourdain², Marie-Annick Clavel², Maurice Enriquez-Sarano¹.
¹Mayo Clinic, Rochester, MN, USA, ²Laval University, Quebec, QC, Canada.

9.35 - 9.45

A34. Prognostic Value of Longitudinal Strain in Asymptomatic Aortic Stenosis and Preserved Left ventricular Ejection Fraction - The COFRASA/GENERAC Study
Maria Melissopoulou, Virginia Nguyen, Tiffany Mathieu, David Attias, Julien Dreyfus, Isabelle Codogno, Alec Vahanian, David Messika-Zeitoun.
Bichat Claude Bernard Hospital, Paris, France.

9.45 - 9.55

A35. Non-Invasive Assessment of Paravalvular Aortic Regurgitation Following Transcatheter Aortic Valve Replacement Based on Energy Loss
Ali N. Azadani¹, Peyman N. Azadani².
¹University of Denver, Denver, CO, USA, ²University of Utah School of Medicine, Salt Lake City, UT, USA.

Concurrent Session V: Heart Valve Outcomes II Keynote & Abstracts

Moderator:

Jose Pomar, MD

8.30 - 8.45

Keynote
Jose Pomar, MD

8.45 - 8.55

A36. Early Versus Delayed Surgery for Patients with Valvular Infective Endocarditis Complicated by Embolic Ischemic Cerebrovascular Events: A Meta-Analysis of 14 Studies
Christos G. Mihos¹, Andres M. Pineda², Orlando Santana².
¹Massachusetts General Hospital, Boston, MA, USA, ²Coulmbia University, Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, FL, USA.

8.55 - 9.05

A37. Matched Comparison of Self Expanding Transcatheter Heart Valves for the Treatment of Failed Surgical Aortic Bioprosthesis: Insights from the Valve in Valve International Data (VIVID) Registry.
Sami M. Alnasser¹, Asim Cheema¹, Ran Kornowski², Matheus Simonato³, Thomas Walther⁴, Azeem Latib⁵, Luca Testa⁶, JeanClaude Laborde⁷, David Hildick Smith⁸, Marco Barbanti⁹, WonKeun Kim¹⁰, Francesco Bedogni¹¹, Hafid Amrane¹², A. J. van Boven¹³, Marc Pelletier¹⁴, Josep RodesCabau¹⁵, Joelle Kefer¹⁶, Christian Frerker¹⁷, Nicolas M Van Mieghem¹⁸, Ganesh Manoharan¹⁹, Stephen G Worthley²⁰, Anita W Asgar²¹, carmelo sgroi²², John Webb²³, Danny Dvir²⁴.
¹University of Toronto, Toronto, ON, Canada, ²Rabin Medical Center, Tel Aviv, Israel, ³Escola Paulista de Medicina, Sao Paulo, Brazil, ⁴Kerckhhoff Heart Center, Bad Nauheim, Germany, ⁵Ospedale San Raffaele, Milan, Italy, ⁶Istituto Clinico S. Ambrogio, Milan, Italy, ⁷St.George hospital, London, Plumtree Nottingham, United Kingdom, ⁸Royal Sussex County Hospital, Brighton, United Kingdom, ⁹Ferrarotto Hospital, University of Catania, Catania, Italy, ¹⁰Kerckhoff Heart Center, Bad Nauheim, Germany, ¹¹Istituto Clinico S Ambrogio, Milan, Italy, ¹²Medisch Centrum, Leeuwarden, Netherlands, ¹³Medisch Centrum Leeuwarden, Leeuwarden, Netherlands, ¹⁴New Brunswick Heart Center, Saint John, NB, Canada, ¹⁵Quebec Heart and Lung Institute, Laval, QC, Canada, ¹⁶Cliniques SaintLuc, Université Catholique de Louvain, Brussels,, Belgium, ¹⁷Asclepios Clinic St. Georg, Hamburg, Germany, ¹⁸Erasmus MC, Rotterdam, Rotterdam, Netherlands, ¹⁹Royal Victoria Hospital, Belfast, United Kingdom, ²⁰The University of Adelaide,, Adelaide, Australia, ²¹Montreal Heart Institute, Montreal, QC, Canada, ²²FERRAROTTO'S HOSPITAL,, CATANIA, Italy, ²³St Pauls Hospital, Vancouver, BC, Canada, ²⁴St Paul's Hospital, Vancouver, BC, Canada.

9.05 - 9.15

A38. Transcatheter Mitral Valve Implantation: One Year Outcomes of the First-In-Man Experience with an Apically Tethered Device
Alison Duncan, Cesare Quarto, Simon Davies, Anselm Uebing, Neil Moat.
The Royal Brompton Hospital, London, United Kingdom.

9.15 - 9.25

A39. Conventional Mitral Valve Surgery in MitraClip Candidates
Thilo Noack, Yamen Al Ghanam, Philipp Kiefer, Fabian Emrich, Philipp Lurz, David M. Holzhey, Farhad Bakhtiary, Martin Misfeld, Gerhard Schuler, Friedrich-Wilhelm Mohr, Joerg Seeburger.
Heart Center Leipzig University, Leipzig, Germany.

9.25 - 9.35

A40. Epidemiology of Valvular Heart Diseases: A 30-year Retrospective of Hospitalizations and In-Hospital Mortality in New York State
Phyllis G. Supino, EdD, Ofek Y. Hai, DO, Jeffrey S. Borer, MD.
SUNY Downstate Medical Center, Beverly, MA, USA.

9.35 - 9.45

A41. Right Ventricular Function by Speckle Tracking and Outcomes In Low-flow, Low Gradient Aortic Stenosis with Low LVEF
Abdellaziz Dahou¹, Marie-Annick Clavel¹, Romain Capoulade², Philipp E. Bartko², Julien Magne³, Gerald Mundigler⁴, Jutta Bergler-Klein⁴, Ian Burwash⁵, Julia Mascherbauer⁴, Henrique B. Ribeiro¹, Kim O'Connor¹, Helmut Baumgartner⁶, Mario Senechal¹, Jean G. Dumesnil⁷, Raphael Rosenhek⁴, Josep Rodés-Cabau¹, Philippe Pibarot¹.
¹QUÉBEC HEART-LUNG INSTITUTE, QUÉBEC, QC, Canada, ²Massachusetts General Hospital, Boston, MA, USA, ³Centre Hospitalier Universitaire Limoges, Limoges, France, ⁴Division of Cardiology, Medical University of Vienna, Vienna, Austria, ⁵University of Ottawa Heart Institute, Ottawa, ON, Canada, ⁶Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany, ⁷Laval University, QUÉBEC, QC, Canada.

9.45 - 9.55

A42. Does The Use Of A Decision Aid Improve Decision Making In Prosthetic Heart Valve Selection? A Multicenter Randomized Clinical Trial
Nelleke M. Korteland¹, Yunus Ahmed², David R. Koolbergen², Marjan Brouwer³, Frederiek de Heer³, Jolanda Kluin³, Eline F. Bruggemans⁴, Robert J.M. Klautz⁴, Anne M. Stiggelbout⁴, Jeroen J.J. Bucx⁵, Ad J.J.C. Bogers¹, Johanna J.M. Takkenberg¹.
¹Erasmus MC, Rotterdam, Netherlands, ²AMC, Amsterdam, Netherlands, ³UMC Utrecht, Utrecht, Netherlands, ⁴LUMC, Leiden, Netherlands, ⁵Diakonessenhuis, Utrecht, Netherlands.

10:00 - 10:30

Coffee Break & Poster Viewing

10.30 - 12.00

Concurrent Session I: Dystrophic Aortic Insufficiency: Limits of Current Guidelines

Moderators:

Emmanuel Lansac, MD
Jean Louis Vanoverschelde, MD

10.30 - 10.40

The LV dysfunction in AR: New ways to assess and decide when to operate?
Linda Giliam, MD

10.40 - 10.50

Quantification of AR: the heart of the matter
Marta Sitges, MD

10.50 - 11.00

Aortic root aneurysm: How to measure, when and how to operate
Thoralf M Suundt, MD

11.00 - 11.10

MRI Aortic Compliance and Risk of Dissection
Emilie Bollache, MD

11.10 - 11.20

Tricuspid aortic valve reapir: Is It Worthwile?
Jan Vojacek, MD

11.20 - 11.30

Bicuspid aortic valve repair: Is It Worthwhile?
Ismail El-Hamamsy, MD

Concurrent Session II: Mitral Valve Prolapse: Clinical & Basic Science

Moderators:

Susan Slaugenhaupt, MD
Russell Norris, MD
Robert Levine, MD

10.30 - 10.42

Serotonergic Regulation of Mitral Valve Prolapse
Robert Levy, MD

10.42 - 10.54

Identification of the Cilia Gene, DZIP1, in a large family with Non-syndromic MVP
David Milan, MD

10.54 - 11.06

Genetic Landscape and Sporadic Mitral Valve Prolapse: Unifying Concepts for Disease Etiology?
Nabila Bouatia-Naji, MD

11.06 - 11.18

Familial MVP Studies Lead to New Candidate Disease Genes
Jean-Jacques Schott, MD

11.18 - 11.30

Translating Genetic and Biological Discoveries into Remidial Therapies for MVP
Roger Markwald, MD

11.30 - 12.00

Discussion

Concurrent Session III: Achieving Regulatory Approval

Moderators:

Jeffrey S. Borer, MD
Wei Sun, Ph.D

10.30 - 10.40

Medical Device Regulatory Essentials: Approval pathways for indication expansions and sub-populations?
Nicole Ibrahim, MD

10.40 - 10.50

Preclinical and Bench Testing - What Can be Inferred?: New Technical Developments
Changfu Wu, PhD

10.50 - 11.00

What can we expect from VARC-3?

11.00 - 11.10

ISO Guidances for Industry and Regulatory Approval Standards: How do They Intersect? Role of modeling
Francis Duray, PhD

11.10 - 11.20

The CE Mark Process - Feasibility Demonstration or Proof of Performance/Safety? How to Select Minimal Sample Sizes?
Bassil Akra, MD

11.20 - 11.30

How Does Industry Respond to Development Issues Involving Two Disparate Approval Systems

11.30 - 12.00

Discussion

Concurrent Session IV: Mechanical Valve & Anticoagulation

Moderators:

Hector Michelena, MD
Sabrina Phillips MD
Bernard Lung, MD

10.30 - 10.45

Mechanical Valve and Pregnant: What to do?
Sabrina Phillips, MD

10.45 - 11.00

New Anticoagulants and Mechanical Valves: Compatible?
Waldemar Wysokinski, MD

11.00 - 11.15

Do Mechanical Valves Thrombose More Than Bioprostheses?
Sorin Pislar, MD

11.15 - 11.30

Can I recommend a lower INR target or aspirin and clopidogrel?
John Puskas, MD

11.30 - 12.00

Discussion

Concurrent Session V: Minimally Invasive Valve Surgery Keynote & Abstracts

Moderator:

W. Randolph Chitwood, MD

10:30 - 10:45

Keynote
W. Randolph Chitwood, MD

10.45 - 10.55

A43. Minimal Invasive and Sutureless Technology: Are These Advantages for Patients Undergoing Aortic Valve Replacement?
Steffen Pfeiffer, Joachim Sirch, Jurij M. Kalisnik, Ferdinand Vogt, Theodor Fischlein, Giuseppe Santarpino.
Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.

10.55 - 11.05

A44. Minimally Invasive Versus Conventional Extracorporeal Circulation In Minimally Invasive Mitral Valve Surgery
Christian J. Rustenbach, Ulrich F.W. Franke, Ragi Nagib, Samir Ahad, Adrian Ursulescu, Hardy Baumbach.
Robert-Bosch-Hospital, Stuttgart, Germany.

11.05 - 11.15

A45. Minimally Invasive Mitral Valve Surgery: Technique of Choice for Cardiac Reoperations
Davide Ricci, Cristina Barbero, Giovanni Marchetto, Suad ElQarra, Massimo Boffini, Mauro Rinaldi.
AOU Città della Salute e della Scienza di Torino - University of Turin, Turin, Italy.

11.15 - 11.25

A46. Transcatheter Aortic Valve Replacement in Patients with Pulmonary Hypertension
Mohammad Rajaei¹, Jose Condado², Hanna Jensen¹, Jose Binongo³, Chandan Devireddy², Bradley Leshnower¹, Jessica Forcillo¹, Stamatios Lerakis², Eric Sarin¹, Kreton Mavromati², Robert Guyton¹, James Stewart², Peter Block², Lillian Tsai¹, Amy Simone¹, Patricia Keegan¹, Vasilis Babaliaros², Vinod Thourani¹.
¹Emory Structural Heart and Valve Center, Joseph B. Whitehead Department of Surgery, Division of Cardiothoracic Surgery, Atlanta, GA, USA, ²Emory Structural Heart and Valve Center, Department of Medicine, Division of Cardiology, Atlanta, GA, USA, ³Emory University Rollins School of Public Health, Atlanta, GA, USA.

11.25 - 11.35

A47. Is there an Impact on Postoperative Morbidity and Long Term Survival after Minimal Access Aortic Valve Replacement
Sven Lehmann, Denis R. Merk, Sergey Leontyev, Christian Etz, Martin Misfeld, Martin Haensig, Anna K. Funkat, Jens Garbade, Friedrich W. Mohr.
Heartcenter Leipzig, Leipzig, Germany.

11.35 - 11.45

A48. New Transcervical Approach to Transcatheter Mitral Valve Replacement (TMVR) using CoreVista System
Cristiano Spadaccio, Fraser W. Sutherland.
Golden Jubilee National Hospital, Glasgow, United Kingdom.

11.45 - 11.55

A49. Aortic Valve Replacement via Right Mini-Thoracotomy: Is it Really Minimally Invasive?
Mauro Del Giglio, Simone Calvi, Simone Turci, Marco Pagliaro, Marco Panzavolta, Elisa Mikus.
Maria Cecilia Hospital, GVM for Care & Research, Cotignola (Ra), Italy.

12:00 - 13:30

Industry Lunch Symposium

13.30 - 15.00

Concurrent Session I: Great Debates

13.30 - 14.15

Debate I: Robotic

Moderators:

Husam Balkhy, MD
Rakesh Suri, MD

13.30 - 13.45

I Do Not Need Robotic Approach

David Adams, MD

13.45 - 14.00

Patients Adore Robotic Repair

Doug Murphy, MD

14.00 - 14.15

Reconciliation with moderators

14.15 - 15.00

Debate II: Low Gradient Normal EF Severe Aortic Stenosis

Moderator:

David Messika-Zeitoun, MD
Maurice Enriquez-Sarano, MD

14.15 - 14.30

Severe AS Low-Gradient Does Not Exist

Jene Louis Vanoverschelde, MD

14.30 - 14.45

Severe AS Low-Gradient Is Genuine and Requires Treatment

Phillippe Pibarot, DVM, PhD

14.45 - 15.00

Reconciliation with moderators

Concurrent Session II: Ischemic Functional MR: New Paradigms From Mechanism to Treatment

Moderators:

Nozomi Watanabe, MD
Judy Hung, MD

13.30 - 13.42

How Big is the Problem? Demographics and Prognosis of Ischemic Functional MR?
Judy Hung, MD

13.42 - 14.00

Secondary/Ischemic/Functional/Type 3b? How Do We Define and Recognize It? Imaging Features
Nozomi Watanabe, MD

Who Should We Fix? How Should We Fix It? Lessons Learned from the CTSN Trials:

14.00 - 14.15

Severe MR
Michael Acker, MD

14.15 - 14.30

Moderate MR
Robert Michler, MD

14.30 - 14.45

Subvalvular Approaches to MV Repair for Ischemic MR
Gorav Ailawadi, MD

14.45 - 15.00

Discussion

Concurrent Session III: Transcatheter Valve Implantation in Failed Bioprostheses/Rings: The Valve-in-Valve Approach

Moderators:

Danny Dvir, MD
Elaine Tseng, MD

13.30 - 13.40

Failure of Surgical Valves: The Scope of the Problem
Marie Annick Clavel, MD

13.40 - 13.50

In Vitro Assessment of Edwards Sapien XT vs. Medtronic Corevalve in Surgical Bioprostheses
Ulrich Steinseifer, MD

13.50 - 14.00

Introduction to Valve-In-Valve Therapies: What Does Clinical Data Show?
Danny Dvir, MD

14.00 - 14.10

Elevated Gradients: The "Achilles' Heel" of Valve in Valve Procedures
Sabine Bleiziffer, MD

14.10 - 14.20

Mitral Valve in Valve/Valve in Ring
Ehud Rannani, MD

14.20 - 14.30

Tricuspid Valve in Valve/Valve in Ring
TBD

14.30 - 15.00

Discussion

Concurrent Session IV: Basic Science to Elucidate Mechanisms of Valve Disease Keynote & Abstracts

Moderators:

Elena Aikawa, MD

13:30 - 13:45

Keynote Speaker
Elena Aikawa, MD

13.45 - 13.55

A50. Cadherin-11 Coordinates Cellular Migration and Extracellular Matrix Remodeling During Aortic Valve Development and Promotes Calcification in Mature Aortic Valves
Derek C. Sung, Caitlin J. Bowen, Kiran A. Vaidya, Jonathan T. Butcher.
Cornell University, Meinig School of Biomedical Engineering, Ithaca, NY, USA.

13.55 - 14.05

A51. Overexpression Of Long Non-coding Rna During Calcific Aortic Valve Stenosis Promotes An Osteogenic Program By Modifying The Epigenetic Signature Of Notch1
Fayez Hadji¹, Marie-Chloé Boulanger¹, Émilie Lavoie-Charland¹, Nathalie Gaudreault¹, Sandra Guauque-Olarte¹, Rihab Bouchareb¹, Mohamed Nsaibia¹, Luigi Bouchard², Yohan Bossé¹, Patrick Mathieu¹.
¹Quebec Heart and Lung Institute, Quebec, QC, Canada, ²Department of biochemistry, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.

14.05 - 14.15

A52. Implication of Leptin in The Development of Calcific Aortic Valve Disease: Induction of Osteoblast Differentiation of Human Valvular Interstitial Cells Via the Akt And Erk Pathways
Mickael Rosa¹, Rodrigo Lorenzi¹, Ahmed Elkalioubie², Madjid Tagzirt¹, Ramadan Jashari³, Francis Juthier², Antoine Rauch², Anaïs Arbesu y Miar¹, Delphine Corseaux¹, André Vincentelli², Bart Staels¹, Eric Van Belle², Sophie Susen², Annabelle Dupont².
¹European Genomic Institute for Diabetes (E.G.I.D.), FR 3508, UNIV LILLE, Inserm UMR 1011; Institut Pasteur de Lille, F-59000, Lille, France, ²European Genomic Institute for Diabetes (E.G.I.D.), FR 3508, UNIV LILLE, Inserm UMR 1011; Institut Pasteur de Lille, F-59000, Cardiovascular and Pulmonary, and Haematology Department, CHRU de Lille, Lille, France, ³European Homograft Bank, c/o Military Hospital Queen Astrid, Brussels, Belgium.

14.15 - 14.25

A53. Shear-Sensitive miRNA-181b Impairs Anti-Inflammatory Signaling in the Aortic Valve Endothelium
Jack Heath, Joan Fernandez Esmerats, Rachel Simmons, Sandeep Kumar, Hanjoong Jo.
Emory University, Atlanta, GA, USA.

14.25 - 14.35

A54. A Role for the Retinoblastoma Pathway in Aortic Valve Disease
Marina Freytsis¹, Lauren Baugh², Phil Hinds¹, Lauren Black², Gordon Huggins³.
¹Tufts University, Boston, MA, USA, ²Tufts University, Medford, MA, USA, ³Tufts Medical Center, Boston, MA, USA.

14.35 - 14.45

A55. GWAS of Aortic Stenosis (AS) in patients with Bicuspid Aortic Valve (BAV) Disease
Mahyar Heydarpour, PhD¹, Vanessa Monteiro-Vieira, BSc¹, Karam Habchi, BSc¹, Jan Sliwa, MD², Martin Sigurdsson, MD, PhD¹, Jochen Muehlschlegel, MD, MMSc¹, Prem Shekar, MD³, Eric Isselbacher, MD⁴, Thoralf Sundt, MD⁴, Simon Body, MBChB, MPH¹.
¹Brigham & Women's Hospital, Perioperative Genomics Center, Boston, MA, USA, ²Brigham & Women's Hospital, Cardiothoracic Anaesthesia, Boston, MA, USA, ³Brigham & Women's Hospital, Heart & Vascular Center, Boston, MA, USA, ⁴Massachusetts General Hospital, Corrigan Minehan Heart Center, Boston, MA, USA.

14.45 - 14.55

A56. Genetic Association and Functional Studies Identifies GLIS1 as A Risk Locus for Mitral Valve Prolapse
Christian Dina¹, Nathan Tucker², Francescaca Delling³, Susan Slaugenhaupt⁴, Robert A. Levine⁵, Albert A. Hagège⁶, Jean-Jacques Schott⁷, Xavier Jeunemaitre⁸, David Milan², Russell Norris⁹, Nabila Bouatia-Naji¹⁰.
¹Inserm UMR1087, CNRS UMR 6291, Institut du Thorax, Centre Hospitalier Universitaire (CHU), Nantes, France, ²Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA, USA, ³Framingham Heart Study, Framingham, MA, USA, ⁴Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, ⁵Cardiac Ultrasound Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, ⁶AP-HP, Department of Cardiology, Hôpital Européen Georges Pompidou, INSERM UMR 970 l Européen Georges Pompidou, INSERM UMR970, Paris, France, ⁷Inserm UMR1087, CNRS UMR 6291, Institut du Thorax, Centre Hospitalier Universitaire (CHU) Nantes, Nantes,, Nantes, France, ⁸AP-HP, Departement of Genetics, Hopital Europeen Georges Pompidou, INSERM U970 Paris Cardiovascular Research Center, Paris, France, ⁹Cardiovascular Developmental Biology Center, Children's Research Institute, Medical University of South Carolinach Institute, Medical University of South Carolina, Charleston, SC, USA, ¹⁰INSERM UMR970 Paris Cardiovascular Research Center, Paris, France.

Concurrent Session V: Percutaneous Heart Valve Therapy Keynote & Abstracts

Moderator:

Michael Mack, MD

13.30 - 13.45

Keynote
Michael Mack, MD

13.45 - 13.55

A57. Transcatheter Tricuspid Valve Repair: Initial Results from the Multicentre First-in-Man Feasibility Trial
Alec Vahanian¹, Francesco Maisano², Jean-Michel Juliard¹, Ottavio Alfieri³, Antonio Colombo³, Antonio L. Bartorelli⁴, Francesco Alamanni⁴, Azeem Latib³.
¹Hôpital Bichat, Université Paris-Diderot, Paris, France, ²University Hospital Zurich, Zurich, Switzerland, ³San Raffaele University Hospital, Milan, Italy, ⁴Centro Cardiologico Monzino, I.R.C.C.S., University of Milan, Milan, Italy.

13.55 - 14.05

A58. Crimp Induced Leaflet Damage and Calcification of Transcatheter Heart Valves
Aditi Sinha¹, Oleksandr Barannyk², Arash Kheradvar¹.
¹University of California, Irvine, Irvine, CA, USA, ²ViVitro Labs Inc, Victoria, BC, Canada.

14.05 - 14.15

A59. Transcatheter Replacement of Failed Bioprosthetic Valves: Comprehensive In-Vitro Bench Testing and Large In-Vivo Clinical Assessment of the Effect of Implantation Depth on Hemodynamics after Valve-in-Valve
Matheus Simonato¹, John Webb¹, Ran Kornowski², Alec Vahanian³, Christian Frerker⁴, Henrik Nissen⁵, Sabine Bleiziffer⁶, Alison Duncan⁷, Guilherme F. Attizzani⁸, Eric Horlick⁹, Azeem Latib¹⁰, Raffi Bekeredjian¹¹, Marco Barbanti¹², Thierry Lefevre¹³, Alfredo Cerillo¹⁴, Jose Maria-Hernandez¹⁵, Giuseppe Bruschi¹⁶, Kostantinos Spargias¹⁷, Alessandro Iadanza¹⁸, Stephen Brecker¹⁹, Jose Honorio Palma²⁰, Ariel Finkelstein²¹, Mohamed Abdel-Wahab²², Pedro Lemos²³, Anna Sonia Petronio²⁴, Didier Champagnac²⁵, Jan-Malte Sinning²⁶, Stefano Salizzoni²⁷, Massimo Napodano²⁸, Claudia Fiorina²⁹, Antonio Marzocchi³⁰, Martin Leon³¹, Danny Dvir¹.
¹St. Paul's Hospital, Vancouver, Canada; ²Rabin Medical Center, Petah Tivka, Israel; ³Hôpital Bichat-Claude Bernard, Paris, France; ⁴Asklepios Klinik, Hamburg, Germany; ⁵Odense University Hospital, Odense, Denmark; ⁶Deutsches Herzzentrum München, Munich, Germany; ⁷Royal Brompton and Harefield, London, United Kingdom; ⁸Case Western Research University, Cleveland, United States; ⁹Peter Munk Cardiac Centre, Toronto, Canada; ¹⁰Ospedale San Raffaelle, Milan, Italy; ¹¹Universitätsklinikum Heidelberg, Heidelberg, Germany; ¹²Ospedale Ferrarotto, Catania, Italy; ¹³Hôpital Jacques Cartier, Massy, France; ¹⁴L'Ospedale del Cuore G. Pasquinucci, Massa, Italy; ¹⁵Hospital Universitario Virgen de la Victoria, Malaga, Spain; ¹⁶Ospedale Niguarda Ca' Granda, Milan, Italy; ¹⁷Hygeia Hospital, Athens, Greece; ¹⁸Azienda Ospedaliera Universitaria Senese, Siena, Italy; ¹⁹St. George's Hospital, London, United Kingdom; ²⁰Escola Paulista de Medicina - UNIFESP, Sao Paulo, Brazil; ²¹Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; ²²Segeberger Kliniken, Bad Segeberg, Germany; ²³Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; ²⁴Università di Pisa, Pisa, Italy; ²⁵Clinique du Tonkin, Villeurbanne, France; ²⁶Universitätsklinikum Bonn, Bonn, Germany; ²⁷Città della Salute e della Scienza - Molinette Hospital, Torino, Italy; ²⁸Università degli Studi di Padova, Padova, Italy; ²⁹Spedali Civili di Brescia, Brescia, Italy; ³⁰Policlinico Sant'Orsola Malpighi, Bologna, Italy; ³¹Columbia University Medical Center, New York, United States.

14.15 - 14.25

A60. Mitral Valve Reconstruction with the Cardioband System: Results of the Multicentre Feasibility Trial
Francesco Maisano¹, Karl-Heinz Kuck², Ottavio Alfieri³, Antonio Colombo³, Stephan Baldus⁴, Alec Vahanian⁵, Georg Nickenig⁶.
¹University Hospital Zurich, Zurich, Switzerland, ²Asklepios Klinik St. Georg Hospital, Hamburg, Germany, ³San Raffaele University Hospital, Milan, Italy, ⁴University Hospital Köln, Cologne, Germany, ⁵Assistance Publique-Hôpitaux de Paris, Bichat Hospital, Paris, France, ⁶University Hospital Bonn, Bonn, Germany.

14.25 - 14.35

A61. Frame Flexibility Effects on Leaflet Stress Distribution: Comparison of Transcatheter versus Surgical Aortic Valve Bioprostheses
Mostafa Abbasi, Mohammed Barakat, Koohyar Vahidkhah, Ali Azadani.
University of Denver, Denver, CO, USA.

14.35 - 14.45

A62. Sinus Flow Stasis Occurs in Valve in Valve Transcatheter Aortic Valve Implantation
Lakshmi P. Dasi¹, Hoda Hatoum¹, Brandon Moore¹, Pablo Maureira², Juan Crestanello¹.
¹The Ohio State University, Columbus, OH, USA, ²Lorraine University Hospital of Nancy, Nancy, France.

14.45 - 14.55

A63. Systematic Transoesophageal Echocardiography after Mitral Valve Replacement - Prevalence and Determinants of Periprosthetic Leakage
Verdonk Constance.
Hopital Bichat, Paris, France.

15.00 - 15.30

Coffee Break & Poster Viewing

15.30 - 17.00

Concurrent Session I: Rapid Fire: Aortic Valve & Other Innovations

Moderator:

Carlos Ruiz, MD
Eric Sarin, MD
Michael Borger, MD
Jeorg Seeburger, MD

In-Audience Moderators:

Maurice Sarano, MD
Rakesh Suri, MD

5 min presentation.

15.30 – 15.35

Dangerous Calcium patterns high risk for root rupture
Jonathan Leipsic, MD

15.35 – 15.40

Valve in valve of a severely regurgitant bipoprosthesis
Amit Segev, MD

15.40 – 15.45

DirectFlow TAVR
Charles Davidson, MD

15.45 – 15.50

Portico TAVR
Gregory Fontana, MD

15.50 – 15.55

Jenavalve for aortic insufficiency
Sabine Bleiziffer, MD

15.55 – 16.00

I prefer the transapical approach for TAVR
Kevin Greason, MD

16.00 – 16.05

I can do trans-caval TAVR
Vasilis Babaliaros

16.05 – 16.10

I can do valve in valve in small prostheses
Norman Mangner, MD

16.10 – 16.15

The Claret device To avoid Stroke
Tamim Nazif, MD

16.15 – 16.20

Periprosthetic AR
Paul Sorajja, MD

16.20 – 16.25

Repositioning the TAVR

16.25 – 16.30

4Tech tricuspid technology
Denti Paolo, MD

16.30 – 17.00

Discussion

Concurrent Session II: Valve Disease Registries

Moderators:

Hanneke Takkenberg, MD
Jolanda Kluin, MD

15.30 - 15.45

The MIDA Registry
Francesco Grigioni, MD

15.45 - 16.00

An Update on the Valve-In-Valve Registry
Danny Dvir, MD

16.00 - 16.15

AVIATOR: Lessons Learned and Challenges Ahead
Jolanda Kluin, MD

16.15 - 16.30

BAVCON
Simon Body, MD

16.30 - 17.00

Discussion

Concurrent Session III: Valve Cell Biology & Pathology

Moderators:

Jane Grande-Allen, Ph.D.
Jonathan Butcher, MD

15.30 – 15.42

Microenvironmental Cues in the Regulation of Valvular Angiogenesis
Kristyn Masters, Ph.D.

15.42 – 15.54

The role of cell shape on valve interstitial cell biology and function
Kartik Balachandran, Ph.D.

15.54 – 16.06

Cellular heterogeneity in aortic valves: relevance for heart valve tissue engineering
Najma Latif, MD

16.06 – 16.18

Endotheliat mesenchymal transformation in fetal valve maturation and postnatal valve remodeling
Jonathan Butcher, MD

16.18 – 16.30

The basic science behind the phase II clinical trial of Ataciguat to treat moderate CAVD
Jordan Miller, MD

16.30 – 17.00

Discussion

Concurrent Session IV: Tricuspid Valve Disease

Moderator:

Jerry Braun, MD
David Messika-Zeitoun, MD

15.30 - 15.45

Etiology and natural history of Tricuspid regurgitation
Hector Michelena, MD

15.45 - 16.00

Assessment and Quantification of Tricuspid Annulus and Regurgitation
David Messika-Zeitoun, MD

16.00 - 16.15

Organic and functional Tricuspid regurgitation, When and how to Operate
Jerry Braun, MD

16.15 - 16.30

Per-cutaneous Treatment of Tricuspid regurgitation - Where do we stand?
Amit Segev, MD

16.30 - 17.00

Discussion

Concurrent Session V: Atrial Fibrillation

Moderator:

Peter Brady, MD
Hersh Maniar, MD

15.30 - 15.42

Hybrid Approaches to Stand-Alone AF, Ideal Patients and Real World Outcomes
Bart Maesen, MD, PhD

15.42 - 15.54

Concomitant Surgical Ablation in Patients Undergoing Valve Surgery: Risks, Benefits and Outcomes
Hersh Maniar, MD

15.54 - 16.06

Surgical MAZE: What Lesion Sets? What Outcomes?
Ralph Damiano Jr., MD

16.06 - 16.18

AF and Mitral Valve Surgery: When Not To Do A MAZE
Thierry Mesan, MD

16.18 - 16.30

Minimizing Stroke Risk in Patients with "Valvular" AF
Peter Brady, MD

16.30 - 17.00

Discussion

17.00 - 18.00

Hand-on Session

18:00 - 19:00

Faculty Reception

SATURDAY, MARCH 19

8:20 - 8:30

Award Presentations for Best Abstracts
Maurice E. Sarano, MD
President
Gilles D. Dreyfus, MD
President-Elect
Michael A. Borger, MD
Past President

8.30 - 10.00

Concurrent Session I: Case Studies I

Moderator:

Maurice E. Sarano, MD

8.30 - 8.40

C1. Redo Transapical Procedure in a Calcified Transapical Edwards Sapien XT Prosthesis
Doreen Richardt, Thorsten Hanke, Holger Thiele, Hans H. Sievers, Thomas Kurz.
University Hospital of Schleswig-Holstein, Lübeck, Germany.

8.40 - 8.50

C2. Three-Dimensional Transoesophageal-Guided Transmitral Valve Implantation with a TENDYNE Device
Alison Duncan, Cesare Quarto, Simon Davies, Neil Moat.
The Royal Brompton Hospital, London, United Kingdom

8.50 - 9.00

C3. Reversible Thrombotic Aortic Restenosis After Valve-In-Valve Transcatheter Aortic Valve Replacement
Patrick J. Goleski, Creighton W. Don, MD.
University of Washington, Seattle, WA, USA.

9.00 - 9.10

C4. Hyper-acute Early Transcatheter Prosthesis Thrombosys In A Patient With Polycythemia Vera.
Laura Besola, Augusto D'Onofrio, Eleonora Bizzotto, Erica Manzan, Chiara Tessari, Gianbattista Isabella, Gaetano Thiene, Gino Gerosa.
University of Padua, Padua, Italy.

9.10 - 9.20

C5. Transcatheter Aortic Valve Replacement in Type B Aortic Dissection
Iosif Gulkarov¹, Akanibo Da-Wariboko, MD¹, Ashwad Afzal, MD¹, Arash Salemi, MD², Berhane Worku¹.
¹New York Methodist Hospital, Brooklyn, NY, USA, ²Weill Cornell Medical Center, New York, NY, USA.

9.20 - 9.30

C6. Multiple Valve Surgery For Advanced Rheumatic Heart Disease: Results And Risk Factors In 150 Patients
Zahira Zouizra, Yassin Boukaidi, Rachid El Houati, Drissi Boumzebra.
Ibn Tofail Hospital, MARRAKECH, Morocco.

9.30 - 9.40

C7. Progressive Aortic Valve Stenosis: is it all about the Calcium Deposition?
Geoffrey D. Huntley, B.A., Jeremy J. Thaden, M.D., Marie-Annick Clavel, D.V.M., Ph.D., Maurice E. Sarano, M.D., Vuyisile T. Nkomo, M.D., M.P.H..
Mayo Clinic, Rochester, MN, USA.

9.40 - 9.50

C8. Apical Left Ventricular Mycotic Aneurysm with Prosthetic Aortic Valve Endocarditis.
Kazuyoshi Takagi, Hiroyuki Otsuka, Koichi Arinaga, Koji Akasu, Tohru Takaseya, Takahiro Shojima, Yuichiro Hirata, Kumiko Wada, Satoshi Kikusaki, Keishi Hashimoto, Hiroyuki Tanaka.
Kurume University, Kurume, Japan.

9.50 - 10.00

C9. Concomitant Tricuspid Valve Replacement using an Extracellular Matrix Cylinder and Pulmonary Thromboembolectomy
Sreekumar Subramanian, MD, Joshua S. Hall, MSM, Bryan T. Fisher, Sr, MD.
TriStar Centennial Medical Center, Nashville, TN, USA.

Concurrent Session II: TAVR Imaging & Implementation

Moderators:

Nicolo Piazza, Ph.D., MD
Mirkos Doss, MD

8.30 - 8.42

Pre-Procedure Screening
Jean Buithieu, MD

8.42 - 8.54

Intraprocedure Guidance
Nicolo Piazza, MD

8.54 - 9.06

Modeling of TAVR Implantation and Function
Wei Sun, PhD

9.06 - 9.18

Post Procedure Valve Assessment (e.g. Valve Thrombosis, Prosthetic Valve Function Evaluation)
Gregory Fontana, MD

9.18 - 9.30

Which Valve for Which Patient - A Tailored Imaging Approach
Mirkos Doss, MD

9.30 - 10.00

Discussion

Concurrent Session III: Biomechanics & Mechanobiology

Moderators:

Michael Sacks, MD
Ajit Yoganathan, MD

8.30 - 8.42

Heart Valve Struction and Function: Implications for Valve Disease
Muralidhar Padala, MD

8.42 - 8.54

Multi-Scale Approaches to Heart Valve Function
Michael Sacks, MD

8.54 - 9.06

Heart Valve Biomechanics
Ajit P. Yoganathan, MD

9.06 - 9.18

Heart Valve Extracellular Matrix Function and Performance
Jane Grande-Allen, MD

9.18 - 9.30

Heart Valve Cellular Function
Craig Simmons, MD

9.30 - 10.00

Discussion

Concurrent Session IV: Valve Repair Network

Moderators:

Michael Borger, MD
Rakesh Suri, MD

8.30 – 8.42

Mitral Valve Repair: A Success Story
Gilles D. Dreyfus, MD

8.42 – 8.54

Aortic Valve Repair: Have We Reached the Limit?
Jean Louis Vanoverschelde, MD

8.54 – 9.06

Mitral Repair Network: Critical hemodynamic and LV measures to include

9.06 – 9.18

Anatomic and functional mitral characteristics indispensable to consider in a valve research network
Ottavio Alfieri, MD

9.18 – 9.30

Starting a Valve Repair Network: Lessons Learned
Emmanuel Lansac, MD

9.30 – 10.00

Discussion

Concurrent Session V: Ross/Homograft

Moderators:

Hanneke Takkenberg, MD
Ismail El-Hamamsy, MD

8.30 - 8.45

Surgical Techniques for Pulmonary Autograft Implantation in Adult Patients
Peter Skillington, MD

8.45 - 9.00

Pediatric Ross Operation: Late Outcomes and Determinants of Homograft Durability
Hanneke Takkenberg, MD

9.00 - 9.15

Reoperations After the Ross Procedure: Challenges and Opportunities
Giovanni Battista Luciani, MD

9.15 - 9.30

Toward a Successful Ross Program: Sharing Experiences
Ismail El-Hamamsy, MD

9.30 - 10.00

Discussion

10.30 - 12.00

Concurrent Session I: Case Studies II

Moderator:

Maurice E. Sarano, MD

10.30 - 10.40

C10. The Challenge of Sizing Valsalva Prostheses for Autograft Reinforcement in the Ross Procedure
Alfred Kocher, Claudia Oeser, Martin Andreas, Guenther Laufer.
Medical University of Vienna, Vienna, Austria.

10.40 - 10.50

C11. Right Atrial Myxoma Clinically Mimicking Recurrence Of Mitral Valve Stenosis After Open Mitral Valve Repair For Rheumatic Severe Mitral Stenosis.
Gauranga Majumdar, Surendra Agarwal, Shantanu Pande, Bipin Chandra.
Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

10.50 - 11.00

C12. Successful Bailout Transcatheter Valve Implantation for Prosthetic Aortic Valve Endocarditis During Open Re-do Surgery
Lorenz Hansen, MD, Klaudija Bijuklic, MD, Jan-Hendrik Stripling, MD, Joachim Schofer, MD, PHD, Friedrich-Christian Rieß, MD, PHD.
Albertinen-Krankenhaus, Hamburg, Germany.

11.00 - 11.10

C13. Importance of the Prosthesis Choice in the Valve-in-Valve Era: Role of the Sutureless Perceval Valve
Stefano Moriggia, Igor Belluschi, Andrea Blasio, Nicola Buzzatti, Fabrizio Monaco, Ottavio Alfieri.
San Raffaele University Hospital, Milan, Italy.

11.10 - 11.20

C14. 3d TOE-guided Mitral Valve-in-Valve Procedure
Alison Duncan, Cesare Quarto, Simon Davies, Neil Moat.
The Royal Brompton Hospital, London, United Kingdom.

11.20 - 11.30

C15. Transcatheter Mitral Valve-in-Ring Replacement: A Novel Therapy in a Challenging Case of Symptomatic Mitral Regurgitation
Risheen S. Reejhsinghani, Lucas S. Zier, Mark L. Villalon, Scot H. Merrick, Georg M. Wieselthaler, Atif N. Qasim, Vaikom S. Mahadevan.
University of California, San Francisco, San Francisco, CA, USA.

11.30 - 11.40

C16. Double-Sided Mitral Valve Repair: Transventricular Approach Augmented By Undersized Annuloplasty Via Conventional Left Atriotomy
Kerim Cagli, MD¹, Ali Baran Budak, MD², Kemal Korkmaz, MD², Hikmet Selcuk Gedik, MD², Eren Gunertem, MD¹, Omer Cicek, MD¹, Gokhan Lafci, MD¹, Serdar Gunaydin, MD, PhD².
¹Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey, ²Numune Training and Research Hospital, Ankara, Turkey.

11.40 - 11.50

C17. Transapical Mitral Valve In Ring Procedure: Intraoperative Challenge And Late Complication
Laura Besola, Augusto D'Onofrio, Erica Manzan, Eleonora Bizzotto, Chiara Tessari, Tomaso Bottio, Giuseppe Tarantini, Gino Gerosa.
University of Padua, Padua, Italy.

11.50 - 12.00

C18. Late presentation of Annular Rupture Initially Mimicking Prosthesis Dysfunction after Transcatheter Aortic Valve Implantation.
Sami M. Alnasser, Christopher Fiendle, Jennifer Day, Mark Osten, Robert J Cusimano, Ashish Shah, Eric Horlick.
Peter Munk Cardiac Center, Toronto General Hospital, University of Toronto, Toronto, ON, Canada.

Concurrent Session II: Mitraclip Imaging & Implementation

Moderators:

Paul Sorajja, MD
Madalina Garbi, MD

10.30 - 10.38

How do I know it's on label DMR?
Muhamed Saric, MD

10.38 - 10.46

Differences in Mitraclip technique for DMR vs. FMR
Magnus Settergren, MD

10.46 - 10.54

Unconventional imaging for MitraClip therapy
Rebecca Hahn, MD

11.02 - 11.10

The benefit of implanting multiple clips
Francisco Maisano, MD

11.10 - 11.18

I only need transthoracic echo to guide the procedure
Mani Vannan, MD

11.18 - 11.26

My hardest case as a Mitraclip expert
Saibal Kar, MD

11.26 - 11.32

A surgeon's perspective on performing Mitraclip
Joerg Seeburger, MD

11.32 - 12.00

Discussion

Concurrent Session III: Ventricular Hemodynamics: Imaging & Modeling

Moderators:

Arash Kheradvar, MD
Sorin Pislaru, MD
Jim Thomas, MD
Blasé Carabello, MD

10.30 - 10.45

The role of invasive hemodynamics in the world of advanced imaging
Blasé Carabello, MD

10.45 - 11.00

Deformation imaging in valvular heart disease: ready for prime time
Sorin Pislaru, MD

11.00 - 11.15

The most common imaging pitfalls in VHD: How can we be more quantitative?
Jim Thomas, MD

11.15 - 11.30

Image-based modeling of hemodynamic in heart valve disease
Arash Kheradvar, MD

11.30 - 12.00

Discussion

Concurrent Session IV: InterAmerican Cardiac Society Collaborative Session

Moderators:

Jose Pomar, MD
Gustavo Restrepo, MD

10.30 - 10.42

Echo Screening for Rheumatic Valve Heart Disease: Where Are We?
Andrea Beaton, MD

10.42 - 10.54

Time to Intervention in Rheumatic Mitral Valve Disease
Flavio Tarasoutchi, MD

10.54 - 11.06

Balloon Mitral Valvuloplasty: Going Beyond Valve Morphology
Marcia Barbosa, MD

11.06 - 11.18

Rheumatic Mitral Valve Regurgitation: Can It Be Repaired?
Taweesak Chotivatanapong, MD

11.18 - 11.30

Are We Always Offering the Best to Our Patients? Same in Every Country?
Jose Pomar, MD

11.30 - 12.00

Discussion

Concurrent Session V: Minimally Invasive & Robotic Surgery

Moderators:

Rakesh Suri, MD
Doug Murphy, MD

10.30 - 10.42

Mitral valve repair: the science behind early repair
Theirry Le Tourneau, MD

10.42 - 10.54

Who are the candidates for robotic mitral repair and how do I set up the operation?
Tomislav Mihaljevic, MD

10.54 - 11.06

Robotic repair for all categories of leaflet prolapse complexity?
Robinson Poffo, MD

11.06 - 11.18

What are the short and mid-term outcomes?
Michael Halkos, MD

11.18 - 11.30

Who Should Undertake the Establishment of a Robotic Program?
Vinay Bhadwar, MD

11.30 - 11.42

My Toughest Robotic Mitral Valve Repair
Emiliano Navarra, MD

11.42 - 12.00

Discussion