The Heart Valve Society
2018 Moderated Posters
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Group 1: Innovations in Experimental Valve Science | Back to Top
B01 Mitral Valve Prolapse: A congenital disease of the primary cilia
Katelynn Toomer1, Mengyao Yu2, Diana Fulmer1, Lilong Guo1, Neal Peterson1, Alex Drohan1, Breiona Catching1, Andy Wessels1, Joshua Lipschutz1, Francesca Delling3, Xavier Jeunemaitre2, Christian Dina4, Ryan Collins5, Harrison Brand5, Mike Talkowski5, Rupak Mukherjee6, Simon Body7, Gary Hardiman8, William Da Silveira8, Baolin Wang9, Maire Leyne5, Ronen Durst10, Roger Markwald1, Solena Le Scouranec4, Albert Hagege2, David Milan11, Jean-Jacques Schott4, Thierry Tourneau4, Robert Levine12, Nabila Bouatia-Naji2, Susan Slaugenhaupt5, Chip Norris1.
1Medical University of South Carolina, Charleston, SC, USA, 2INSERM, UMR-970, Paris Cardiovascular Research Center, Paris, France, 3Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, CA, USA, 4Inserm U1087; institut du thorax; University Hospital, Nantes, France, 5Center for Human Genetic Research, Massachusetts General Hospital and Department of Neurology, Harvard Medical School, Boston, MA, USA, 6Gazes Cardiac Research Institute, Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA, 7Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, 8Center for Genomic Medicine, Medical University of South Carolina, Charleston, SC, USA, 9Department of Genetic Medicine, Weill Medical College of Cornell University, New York, NY, USA, 10Cardiology Division, Hadassah Hebrew University Medical Center, Jerusalem, Israel, 11Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA, 12Cardiac Ultrasound Laboratory, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
B02 Serotonin Transporter Polymorphism Genotype Effects in Mitral Valve Prolapse with Severe Regurgitation
Elisa Salvati1, Kathryn H. Driesbaugh2, Juan B. Grau3, Michael A. Acker2, Eric K. Lai2, Nancy Rioux4, Farrah A. Alkhaleel2, Richard E. Shaw4, Abba M. Krieger2, Robert J. Levy1, Giovanni Ferrari5.
1The Children's Hospital of Philadelphia, Philadelphia, PA, USA, 2University of Pennsylvania, Philadelphia, PA, USA, 3Ottawa Heart Institute, Ottawa, ON, Canada, 4The Valley Hospital, Ridgewood, NJ, USA, 5Columbia University, New York, NY, USA.
B03 Pathological Expression of Matrix Metalloproteinases (MMPs) and their Tissue Inhibitors (TIMPs) in a Volume Overloaded Left Ventricle from Chronic Mitral Valve Regurgitation
Daniella Corporan, Daisuke Onohara, Roberto Hernandez-Merlo, Muralidhar Padala.
Emory University, Atlanta, GA, USA.
B04 Mechanically Equivalent Mitral Valve Sub-Valvular Apparatus
Amir H. Khalighi1, Bruno V. Rego1, Andrew Drach1, Robert C. Gorman2, Jospeh H. Gorman, III2, Michael S. Sacks1.
1The University of Texas at Austin, Austin, TX, USA, 2University of Pennsylvania, Philadelphia, PA, USA.
B05 Valve Endothelial Cells Exacerbate Interstitial Cell Calcification Under Mechanical Tension
Terence W. Gee, Jennifer M. Richards, Jonathan T. Butcher.
Cornell University, Ithaca, NY, USA.
B06 Cellular-Scale Sex Bias in ECM and Growth Factor Production
LaTonya Simon, Gabriela Betancourt, Kristyn Masters.
University of Wisconsin-Madison, Madison, WI, USA.
B07 A Porphyrin-based Sod Mimic, Mntnbuoe-2-pyp5+ Inhibits Mechanisms Of Aortic Valve Remodeling In Human And Murine Models Of Aortic Valve Sclerosis
Wanda Anselmo1, Emanuela Branchetti1, Juan B. Grau2, Gen Li3, Salma Ayoub4, Nancy Rioux5, Artak Tovmasyan6, Michael S. Sacks4, Ines Batinic-Haberle6, Robert J. Levy7, Giovanni Ferrari3.
1University of Pennsylvania, Philadelphia, PA, USA, 2Ottawa Heart Institute, Ottawa, ON, Canada, 3Columbia University, New York, NY, USA, 4Texas University at Austin, Austin, TX, USA, 5The Valley Hospital, Ridgewood, NJ, USA, 6Duke University, Durham, NC, USA, 7The Childrens Hospital of Philadlephia, Philadelphia, PA, USA.
B08 Warfarin Accelerates The High Phosphate-induced Calcification Of Human Aortic Valve Interstitial Cells By Elevating Pregnane X Receptor Activity
Zaiqiang Yu, Ikuo Fukuda, Kazuyuki Daitoku, Mari Chiyoya.
Hirosaki University, Aomori, Japan.
 
Group 2: Tissue Engineering for Regenerative Medicine and Modeling Disease | Back to Top
B09 Emergence Of A Geometrical And Mechanical Equilibrium In Tissue-Engineered Heart Valves?
Mathieu A.J. van Kelle, M.Sc, Pim J.A. Oomen, M.Sc, Marloers W.J.T. Janssen–van den Broek, B.Sc, Richard G.P. Lopata, Ph.D, Sandra Loerakker, Ph.D, Carlijn V.C. Bouten, Ph.D.
Eindhoven University of Technology, Eindhoven, Netherlands.
B10 Development of an Off-the-shelf Tissue Engineered Sinus Valve for Transcatheter Pulmonary Valve Replacement
Sarah E. Motta1, Emanuela S. Fioretta1, Petra E. Dijkman1, Valentina Lintas1, Luc Behr2, Simon P. Hoerstrup1, Maximilian Y. Emmert1.
1University of Zurich, Zurich, Switzerland, 2Institute Mutualiste Montsouris, Paris, France.
B11 Regeneration and Immune Response of Engineered Tissue Graft in Non-Human Primate Model
Zeeshan Syedain, Melanie Graham, Ty Dunn, Timothy O'Brien, Sandra Johnson, Robert Schumacher, Robert Tranquillo.
University of Minnesota, Minneapolis, MN, USA.
B12 State of the Art Simulation of Bioprosthetic Heart Valve Durability
Will Zhang, Michael S. Sacks.
The University of Texas at Austin, Austin, TX, USA.
B13 Valve Interstitial Cell Mechanics Within a 3D Poly(ethylene glycol) Hydrogel
Alex Khang1, Andrea Gonzalez Rodriguez2, Megan Schroeder2, Kristi S. Anseth2, Michael S. Sacks1.
1The University of Texas at Austin, Austin, TX, USA, 2University of Colorado at Boulder, Boulder, CO, USA.
B14 Radiation induces loss of Valvular Interstitial Cell Phenotype in 3D Hydrogel Model of Calcific Aortic Valve Disease
Jesper Hjortnaes1, Rob Driessen2, Nicole Van Engeland2, Irith Bergsma2, Jacco Steenhuijsen3, Jolanda Kluin4, David Konozo5, Elena Aikawa6, Carlijn Bouten2.
1University Medical Center Utrecht, Utrecht, Netherlands, 2Technical University Eindhoven, Eindhoven, Netherlands, 3Catherina Hospital Eindhoven, Eindhoven, Netherlands, 4Amsterdam Medical Center, Amsterdam, Netherlands, 5Dana Farber Institute/Brigham and Women's Hospital, Boston, MA, USA, 6Brigham and Women's Hospital, Boston, Netherlands.
B15 Hydroxyapatite Particles Drive Osteogenic Response of 3D-Cultured Aortic Valve Interstitial and Endothelial Cells via a BMP/NFkB-Dependent Pathway
Ablajan Mahmut, Andrea Lo, Xiao Yin Ma, Jennifer Richards, Jae Woong Jang, Jennie Ann Kunitake, Joo ho Kim, Eve Donnelly, Lara A Estroff, Jonathan T Butcher.
Cornell University, ithaca, NY, USA.
B16 Investigating Sex-linked Influence on Calcific Aortic Valve Development Using a 3D Filter Paper Cell Culture Platform
Madeline Monroe, Jane Grande-Allen.
Rice University, Houston, TX, USA.
 
Group 3: Cardiac Imaging | Back to Top
B17 Burden and Clinical Outcome of Tricuspid Regurgitation in Patients with Systolic Dysfunction
Yan Topilsky1, Maurice Enriquez Sarano2.
1Tel Aviv Medical Center, Tel Aviv, Israel, 2Mayo Clinic, Rochester, MN, USA.
B18 Alterations in Aortic Flow after Valve Sparing Root Replacement With or Without Neo-Sinuses Reconstruction
Antonino Di Franco1, Jeremy Leonard1, Ahmed Abouarab1, Filippo Piatti2, Francesco Sturla3, Nicola Galea4, Jonathan W. Weinsaft1, Christopher Lau1, Emiliano Votta2, Ilaria Chirichill5, Ruggero De Paulis5, Leonard N. Girardi1, Alberto Redaelli2, Mario Gaudino1.
1Weill Cornell Medicine, New York City, NY, USA, 2Politecnico di Milano, Milan, Italy, 3IRCCS Policlinico San Donato, San Donato Milanese, Italy, 4Sapienza University, Rome, Italy, 5European Hospital, Rome, Italy.
B19 Left Atrial Minimum Volume Is More Strongly Associated With Left Ventricular Filling Pressures Than The Left Atrial Maximum Volume
Imen Hamdi, Khalil Houissa, Amina Belouaer, Wafa Fehri, Habib Haouala.
Military Hospital of Tunis, Tunis, Tunisia.
B20 Assessment Of Reverse Remodeling Predicted By Myocardial Deformation On Tissue Tracking In Patients With Severe Aortic Stenosis: A Cardiac Magnetic Resonance Imaging Study
Sung-Ji Park1, Ji-Won Hwang1, Sung Mok Kim1, Eun Jeong Cho2, Dong-Ju Choi3, Eun Kyoung Kim1, Sung-A Chang1, San-Chol Lee1, Yeon Hyeon Choe1, Seung Woo Park1.
1Samsung Medical Center, Seoul, Korea, Republic of, 2National Cancer Center, Seoul, Korea, Republic of, 3Seoul National University Bundang Hospital, Seoul, Korea, Republic of.
B21 Prognostic Value of NT Pro BNP in Patients with Functional Mitral Regurgitation: Impact On Decision Making In Non-ischemic Cardiomyopathy
Rodolfo Pizarro, Pablo F. Oberti, Anibal M. Arias, Luciano O. Lucas, Mariano L. Falconi, Cesar A. Belziti.
Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
B22 Clinical And Echocardiographic Correlates Of revalent Atrial Fibrillation And Mortality In Severe Aortic Stenosis
Sindhura Ananthaneni, M.B.B.S, Mackram Eleid, M.D, Vuyisile Nkomo, M.D, Patricia Pellikka, M.D, Jeremy Thaden, M.D.
Mayo clinic, Rochester, MN, USA.
B23 Coexistent Bicuspid Aortic Valve and Mitral Valve Prolapse: Epidemiology and Importance of the Giant Anterior Mitral Leaflet Phenotype
Ratnasari Padang, Sorin V. Pislaru, Joseph F. Malouf, Vuyisile T. Nkomo, Sunil V. Mankad, Simon Maltais, Hartzell V. Schaff, Maurice Enriquez- Sarano, Hector I. Michelena.
Mayo Clinic, Rochester, MN, USA.
B24 The Identification of Suitability for Aortic Valve Plasty Using Three-Dimensional Transesophageal Echocardiography
Haruka Fujimaki, Keitarou Mahara, Kanako Kishiki, Mai Terada, Shuichirou Takanashi.
Sakakibara Heart Institute, Tokyo, Japan.
 
Group 4: Surgical Valve Therapies I | Back to Top
B25 Outcomes after Aortic Valve Replacement with Bioprostheses and Mechanical Prostheses in Elderly Patients: Systematic Review, Meta-analysis, and Patient Level Simulation
Simone A. Huygens1, Jonathan R.G. Etnel1, Milad Hanif1, Gjorgji Kalpak1, Jos A. Bekkers1, Ad J.J.C. Bogers1, Maureen P.M.H. Rutten-van Mölken2, Johanna J.M. Takkenberg1.
1Erasmus MC, Rotterdam, Netherlands, 2Erasmus University Rotterdam, Rotterdam, Netherlands.
B26 Long-term Outcomes of Bioprosthetic Valve Replacement for Structural Valve Degeneration In Aortic and Mitral Position: Implications for Current Choice of a Valvular Substitute
Jerome Jouan1, Alain Carpentier1, Paul Achouh1, Yashutosh Joshi2, Jean-Noël Fabiani1, Philippe Menasché3, Christian Latrémouille1.
1Department of Cardiovascular surgery, Georges Pompidou European Hospital, Assistance Publique - Hopitaux de Paris, University Paris- Descartes, Sorbonne Paris-Cité., Paris, France, 2Blacktown Hospital, Sidney, Australia, 3Department of Cardiovascular surgery, Georges Pompidou European Hospital, Assistance Publique - Hopitaux de Paris, University Paris- Descartes, Sorbonne Paris-Cité and INSERM UMR 970., Paris, France.
B27 Mitral Valve Surgery In Octogenarians: Minimally Invasive Could Be Better
Davide Ricci, Erik Cura Stura, Giovanni Marchetto, Suad ElQarra, Massimo Boffini, Mauro Rinaldi.
AOU Città della Salute e della Scienza di Torino - University of Turin, Turin, Italy.
B28 Tricuspid Valve Replacement In Patients With Carcinoid Heart Disease: Are Outcomes After Mechanical Prostheses Favorable?
Kevin M. Veen, Frans B.S Oei, Peter L. de Jong, Annemien E. van de Bosch, Wouter W. de Herder, Johanna J.M Takkenberg, Ad J.J.C. Bogers.
Erasmus MC, Rotterdam, Netherlands.
B29 Aortic Symmetry Index : Initial Validation of a Novel Preoperative Echo Predictorof Recurrent Aortic Regurgitation after Aortic Valve Repair
Lisa Q. Rong, Antonino DiFranco, Jonathan W. Weinsaft, Mario FL Gaudino, Leonard N. Girardi.
Weill Cornell Medicine, New York, NY, USA.
B30 Early and 1-Year Clinical and Hemodynamic Outcomes Following Aortic Valve Replacement with Rapid Deployment Bioprostheses
Chiara Tessari, Annalisa Francescato, Giorgia Cibin, Lorenzo Bagozzi, Rita Pesce, Augusto D'Onofrio, Gino Gerosa.
Cardiac Surgery Unit, Padova, Italy.
B31 Surgical Treatment of the Ascending Aortic Aneurysm Associated with Aortic Regurgitation by Correction of the Aortic Root Geometry and Relocation of the Aortic Valve Plane
Grigore Tinica1, Mihail Enache1, Raluca Ozana Chistol1, Cristina Furnica2.
1Cardiovascular Diseases Institute, Iasi, Romania, 2University of Medicine and Pharmacy, Iasi, Romania.
B32 Outcome After Bioprosthetic Aortic Valve Replacement in Young Adults: a Systematic Review, Meta-Analysis and Microsimulation
Jonathan R.G. Etnel, Pepijn Grashuis, Begüm Pekbay, Simone A. Huygens, Grigorios Papageorgiou, Jolien W. Roos-Hesselink, Ad J.J.C. Bogers, Johanna J.M. Takkenberg.
Erasmus University Medical Center, Rotterdam, Netherlands.
 
Group 5: Surgical Valve Therapies II | Back to Top
B33 Sutureless Perceval (liva Nova, Saluggia, Italia) Aortic Valve In High Risk Aortic Patients. A Key Tool For The Cardiac Surgeon
Elisabet Berastegui Garcia1, Maria Luisa CAmara Rosell1, Sara Badia Gamarra1, Luis Delgado Ramis1, Claudio Fernandez Gallego1, Ignasi Julià Almill2, Anna Llorens Ferrer2, Christian Muñoz Guijosa2.
1Hospital Universitari Germans Trias i Pujol, badalona, Spain, 2Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
B34 Comparison Of Long-term Results Of Methods Of Surgical Correction Of Mitral Insufficiency With Violating The Integrity Of Chordal-papillary Continuation
Volodymyr Popov.
National Institute of Cardio-Vascular Surgery name of M. M. Amosov, Kyiv, Ukraine.
B35 A Flexible Posterior Leaflet Extending Implant Eliminates Functional Mitral Regurgitation In A Swine Model
Kirthana Suresh, MS, Qi He, Muralidhar Padala.
Emory University, Atlanta, GA, USA.
B36 The Medtronic Freestyle Stentless Bioprosthesis® as a Full Aortic Root - Indications and Intermediate-term Outcomes
Hanna H. Dagnegård, MD, Kirstine Bekke, Nikolaj Ihlemann, MD, PhD, Hans Gustav Hørsted Thyregod, MD, PhD, Jens Lund, MD, Lars Søndergaard, MD, Prof., Morten Smerup, MD, PhD..
Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
B37 Stress Analysis of Transcatheter and Surgical Bioprosthetic Valves: A Comparative Study of SAPIEN 3, CoreValve, and PERIMOUNT Magna
Mostafa Abbasi1, Mohammed Barakat1, Yashar Behnam1, Chadd Clary1, Danny Dvir2, Ali Azadani1.
1University of Denver, Denver, CO, USA, 2University of Washington, Seattle, WA, USA.
B38 Admissions for Infective Endocarditis in Intravenous Drug Users: A Growing Healthcare Cost Crisis
Salil Deo1, Sajjad Raza1, Ankur Kalra1, Vaishali Deo2, Salah E. Altarabsheh3, Alan H. Markowitz1, Joseph F. Sabik, III1, Soon Park1.
1University Hospitals Cleveland Medical Center, Cleveland, OH, USA, 2School of Medicine, Case Western Reserve University, Cleveland, OH, USA, 3Queen Alia Heart Institute, Amman, Jordan.
B39 Evaluating Patients' Experience and quality of life Following Heart Valve Surgery: Examining patients' perspective of The Impact Of Valve Type Choices.
Philemon Gukop, Georgios T. Karapanagiotidis, Rajdeep Bilkhu, Kavitha Mattam, Adnan Charaf, Aziz Momin, Mazin Sarsam, Venkatachalam Chandrasekaran.
St George's University hospital NHS London, London, United Kingdom.
B40 Standardized Aortic Valve Repair For Isolated Aortic Insufficiency Using Single Or Double Ring Annuloplasty
MUSTAFA ZAKKAR, VITO DOMENICO BRUNO, CHRISTOPHE ACAR, NIZAR KHELIL, THIERRY FOLLIGUET, MATHIEU DEBAUCHEZ, EMMANUEL LANSAC.
Institut Mutualiste Montsouris, PARIS, France.
 
Group 6: Transcatheter Therapies | Back to Top
B41 Neo-Sinus Washout Quantification in Transcatheter Heart Valves
David Immanuel Madukauwa-David1, Vahid Sadri1, Prem Midha1, Vrishank Raghav2, Norihiko Kamioka3, Rahul Sharma4, Vasilis Babaliaros3, Ajit Yoganathan1.
1Georgia Institute of Technology, Atlanta, GA, USA, 2Auburn University, Auburn, AL, USA, 3Emory University, Atlanta, GA, USA, 4Cedars-Sinai Heart Institute, Los Angeles, CA, USA.
B42 Transcatheter Retrieval of Mechanical Heart Valves
Paul P. Heinisch1, Ralf Brecht2, Dominik Obrist3, Thierry Carrel1, Ali Khoynezhad4.
1Department of Cardiovascular Surgery, University Hospital Bern, Bern, Switzerland, 2University Hospital Regensburg, Regensburg, Germany, 3ARTORG Center for Biomedical Engineering Research, Bern, Switzerland, 4Division of Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
B43 Transcarotid TAVR: In Hospital and Intermediate Term Clinical Outcomes
Keith B. Allen1, Adnan Chhatriwalla1, John Saxon1, David Cohen1, Zuhair Hawa1, Sanjeev Aggarwal1, Suzanne Baron1, Anthony Hart1, Alexander F. Pak2, Zafir Hawa2, Jim Mitchell2, J. Russell Davis1, A. Michael Borkon1.
1St. Luke's Mid America Heart Institute, Kansas City, MO, USA, 2North Kansas City Hospital, North Kansas City, MO, USA.
B44 Leaflet Restoration - a New Concept for Aortic Valve Replacement
Gregory Fontana1, Christian Spaulding2, Frederick Schoen3, Martijn Cox4, Oleg Svanidze5.
1Los Robles Hospital and Medical Center, Thousand Oaks, CA, USA, 2European Hospital Georges Pompidou, Paris, France, 3Brigham and Women's Hospital, Boston, MA, USA, 4Xeltis BV, Eindhoven, Netherlands, 5Xeltis AG, Zurich, Switzerland.
B45 Impact of Simulated Mitral Clip on Forward Flow Obstruction in the Setting of Mitral Leaflet Tethering: An In Vitro Investigation.
Charles H. Bloodworth, M.S.1, Eric L. Pierce, B.S.1, Keshav Kohli, M.S.1, Nancy J. Deaton1, Kaitlin J. Jones, B.S.1, Radhika Duvvuri, B.S.1, Norihiko Kamioka, M.D.2, Vasilis C. Babaliaros, M.D.2, Ajit P. Yoganathan, PhD1.
1Georgia Institute of Technology and Emory University, Atlanta, GA, USA, 2Emory University School of Medicine, Atlanta, GA, USA.
B46 Post-TAVR Paravalvular Leak Adversely Affects Left Ventricular Kinetic Energy
Daisuke Morisawa, Ahmad Falahatpisheh, Arash Kheradvar.
University of California, Irvine, Irvine, CA, USA.
B47 New Model for the Assessment of Transcatheter Aortic Valve Replacement (TAVR) Devices in Sheep
Yuriy Moklyak, John P. Carney, Matthew T. Lahti, Jill T. Schappa Faustich, Agustin P. Dalmasso, Richard W. Bianco.
University of Minnesota, Minneapolis, MN, USA.
B48 Acute Changes of Mitral Valve Anatomy After Percutaneous Edge- to- Edge Mitral Valve Repair in Degenerative Mitral Regurgitation
Didem Oguz, Mackram Eleid, Sunil Mankad, Sorin Pislaru, Joseph Maalouf, Vuyisile Nkomo, David Holmes, Guy Reeder, Charanjit Rihal, Jeremy Thaden.
Mayo Clinic, Rochester, MN, USA.