HVS - 2022 Annual Scientific Meeting Program

2022 HVS Annual Meeting On Demand Recordings are now available.

Program and Abstracts | ICTEHV | Posters

WEDNESDAY, 2 MARCH 2022

11:30 AM - 3:00 PM

ICTEHV Pre-Meeting

3:00 PM - 5:00 PM

Board of Directors Meeting

6:00 PM - 9:00 PM

Movies & Libations 1: Mitral and Tricuspid Valve
Moderators: Molly Szerlip, MD & Vinod H. Thourani, MD
(7 minute presentation, followed by an 8 minute discussion)

6:00 PM - 6:15 PM

Isolated P2 Prolapse Surgical Repair with Leaflet Resection
Gorav Ailawadi, MD

6:15 PM - 6:30 PM

Barlow's Valve Repair with Neochords
Joseph Lamelas, MD

6:30 PM - 6:45 PM

Repair of a Barlow's Valve with TEER
Molly Szerlip, MD

6:45 PM - 7:00 PM

Transapical Mitral Valve Replacement for FMR
Brian Bethea, MD

7:00 PM - 7:15 PM

Trans-Septal Mitral Valve Replacement for FMR
Vinod H. Thourani, MD

7:15 PM - 7:30 PM

Transapical Mitral Valve Replacement in MAC
Brian Bethea, MD

7:30 PM - 7:45 PM

Surgical Replacement in MAC
Robert Smith, MD

7:45 PM - 8:00 PM

Transcatheter Valve Replacement of Prior MV Repair
Mark Peterson, MD

8:00 PM - 8:15 PM

Transcatheter Valve in Failed Tricuspid Valve Ring
Maurizio Taramasso, MD, PhD

8:15 PM - 8:30 PM

Surgical Tricuspid Valve Repair
Juan Pablo Umana, MD

8:30 PM - 8:45 PM

Tricuspid Valve Repair with TEER
Paul Sorajja, MD

8:45 PM - 9:00 PM

Transfemoral Tricuspid Replacement
Pradeep Yadav, MD

6:00 PM - 9:00 PM

Movies & Libations 2: Aortic Valve and Aorta
Moderators: Jessica Forcillo, MD, Tom C. Nguyen, MD, & Marta Sitges, MD
(7 minute presentation, followed by an 8 minute discussion)

6:00 PM - 6:15 PM

TAVR in A Bicuspid AV
Raj Makkar, MD

6:15 PM - 6:30 PM

TAVR in Small Aortic Root with Coronary Protection
James Stewart, MD

6:30 PM - 6:45 PM

Aortic Valve Replacement with Annular Enlargement
Bo Yang, MD, PhD

6:45 PM - 7:00 PM

TAVR Valve in Valve with BASILICA
Samir Kapadia, MD

7:00 PM - 7:15 PM

Aortic Valve Replacement through Ministernotomy
Sabine Bleiziffer, MD

7:15 PM - 7:30 PM

How To Remove A SEV And BAV TAVR Valve?
Shinichi Fukuhara, MD

7:30 PM - 7:45 PM

TAVR for Aortic Regurgitation
Torsten P. Vahl, MD

7:45 PM - 8:00 PM

How To Perform A Ross Operation?
Ismail El-Hamamsy, MD, PhD

8:00 PM - 8:15 PM

Bentall Procedure
Anthony L. Estrera, MD

8:15 PM - 8:30 PM

Valve Sparing Root Replacement for Trileaflet AV
Maral Ouzounian, MD

8:30 PM - 8:45 PM

Valve Sparing Root Replacement with Bileaftlet AV
Joseph E. Bavaria, MD

8:45 PM - 9:00 PM

Concomitant Transcatheter TAVR and MV Repair
Nicole Karam, MD

THURSDAY, 3 MARCH 2022

7:00 AM - 7:50 AM

BREAKFAST WITH INDUSTRY

8:00 AM - 8:05 AM

Welcome and Opening
Vinod H. Thourani, MD

PLENARY SESSION I: THE ENIGMA OF FUNCTIONAL MITRAL REGURGITATION

8:05 AM - 10:00 AM

Chairs: Jose L. Pomar, MD, Marta Sitges, MD, & Vinod H. Thourani, MD
Panelists: Neil E. Moat, MD, Efi Roe, & All Speakers

8:05 AM - 8:15 AM

Differences in Mitral Valve Regurgitation in the 2020 ACC/AHA and ESC/EACTS 2021 Guidelines
Marta Sitges, MD

8:15 AM - 8:35 AM

Discussion

Focus on Functional MR

8:35 AM - 8:45 AM

Surgical Mitral Valve Replacement is the Gold Standard
Gorav Ailawadi, MD

8:45 AM - 8:55 AM

Surgical Mitral Valve Repair is the Simplest Option
Steven. F. Bolling, MD

8:55 AM - 9:10 AM

Discussion

9:10 AM - 9:20 AM

Transcatheter Replacement Provides the Best of Both Worlds
Susheel Kodali, MD

9:20 AM - 9:30 AM

Putting it all Together and Using my Crystal Ball: How will we be treating FMR in 2030, from Physiology to Patient Preference
Maurice Sarano, MD

9:30 AM - 10:00 AM

Discussion

10:00 AM - 10:30 AM

BREAK WITH INDUSTRY

Breakout Session 1 - Aortic Valve 1

10:30 AM - 12:00 PM

Sub-Clinical Thrombosis and Anti-thrombotic Strategies in AV Surgery
Moderators: Mark J. Russo, MD, Jacob Delarosa, MD

10:30 AM - 10:38 AM

Computational Modeling to Understand and Predict Valve Thrombosis
Prasad Dasi, PhD

10:38 AM - 10:46 AM

Subclinical and Clinical Leaflet Thrombosis of TAVR valves: Implication for life-time management
Raj Makkar, MD

10:46 AM - 10:54 AM

Overview of Trials on Antithrombotic Therapies
George Dangas, MD

10:54 AM - 11:05 AM

Discussion

11:05 AM - 11:15 AM

1. Anatomical Evaluation Of Balloon-expandable Transcatheter Aortic Valve Replacement - Computed Tomography Insights For Hypo-attenuating Leaflet Thickening
Miho Fukui, Vinayak N. Bapat, Santiago Garcia, Hirotomo Sato, Maurice Enriquez-Sarano, John R. Lesser, Joao L. Cavalcante, Paul Sorajja.
Minneapolis Heart Institute Foundation, Minneapolis, MN, USA.

11:15 AM - 11:25 AM

2. Subclinical Leaflet Thrombosis Following Transcatheter Valve-in-valve Procedures: A Comparative Simulation Study Of Sapien 3 And Corevalve
Dong Qiu, Ali Azadani.
University of Denver, Denver, CO, USA.

11:25 AM - 11:33 AM

Novel Antithrombotic Therapies for Mechanical Aortic Valves
Mark W. Gerdisch, MD

11:33 AM - 11:41 AM

Future Valve Designs to Mitigate Valve Thrombosis
Hoda Hatoum, PhD

11:41 AM - 12:00 PM

Discussion

Breakout Session 2 - Mitral Valve 1

10:30 AM - 12:00 PM

Modern Practice for Degenerative Mitral Regurgitation
Moderators: Arnar Geirrson, MD, Rakesh M. Suri, MD & D. Scott Lim, MD

10:30AM - 10:38 AM

Arrhythmogenic Mitral Valve Prolapse and Sudden Cardiac Death
Francesca N. Delling MD

10:38 AM - 10:46 AM

Genetics of Degenerative Mitral Valve Regurgitation
Russel Norris, MD

10:46 AM - 10:54 AM

Beyond the Echo, Advances in MRI MV Imaging
Stamatios Lerakis, MD, PhD

10:54 AM - 11:04 AM

Discussion

11:04 AM - 11:12 AM

Knowledge gaps for Future Research: What We Don't Know about DMR
Patrick T. O'Gara, MD

11:12 AM - 11:20 AM

New Transcatheter Technologies for Primary MR: From Trans-Septal to Transapical
Pradeep Yadav, MD

11:20 AM - 11:28 AM

Deciding on Surgical Techniques for Primary MR: From Resection to Preservation and Beyond
Patrick McCarthy, MD

11:28 AM - 11:40 AM

Discussion

11:40 AM - 11:50 AM

3. Degenerative Mitral Valve Disease: Thoracoscopic Versus Robotic Approach
Elena Sandoval, Anna Muro, Eduard Quintana, Jorge Alcocer, Clemente Barriuso, Jose Luis Pomar, Manuel Castella, Daniel Pereda.
Hospital Clinic, Barcelona, Spain.

11:50 AM - 12:00 PM

4. Hyperactivated Mek/erk Signaling As The Major Disease Initiating Pathway In Mitral Valve Prolapse
Tyler C. Beck¹, Kendra Springs², Jordan Morningstar¹, Cortney Gensemer¹, Leon Guo¹, Rachel Biggs¹, Kelsey Moore¹, Menny Benjamin¹, Natalie Koren¹, Russell Norris¹.
¹Medical University of South Carolina, Charleston, SC, USA, ²College of Charleston, Charleston, SC, USA.

Breakout Session 3 - Congenital 1

10:30 AM - 12:00 PM

Determining What's "Right": New Therapies for Pulmonary Valve Replacement
Moderators: Morten Smerup, MD

10:30 AM - 10:42 AM

Indications for Pulmonary Valve Replacement: What does the Data Show?
Ada Steanescu, MD

10:42 AM - 10:54 AM

New Pulmonary Valve Prototypes and Techniques
Scott Lim, MD

10:54 AM - 11:06 AM

Tricuspid valve repair vs replacement in Ebstein anomaly: Indications and long term-outcomes
Joseph Dearani, MD

11:06 AM - 11:18 AM

Looking to the Future: Creating Personalized Conduits with Stem Cell Therapy
Sunjay Kaushal, MD, PhD

11:18 AM - 11:30 AM

Advances in Surgical Therapies for Pulmonary Valve Replacement Including Hybrid Procedures
Pranava Sinha, MD

11:30 AM - 11:50 AM

Discussion

11:50 AM - 12:00PM

5. Mid-to-long Term Outcomes After Pulmonary Valve Replacement: A Systematic Review And Meta-analysis
Xu Wang, Wouter Bakhuis, Kevin M. Veen, Ad J.J.C Bogers, Jonathan R.G. Etnel, Carlijn C.E.M. van der Ven, Jolien W. Roos-Hesselink, Eleni-Rosalina Andrinopoulou, Johanna J.M. Takkenberg.
Erasmus Medical Center, Rotterdam, Netherlands.

Breakout Session 4 - Proximal Aorta 1

10:30 AM - 12:00 PM

Valve Disease in Patients with Connective Tissue Disorders
Moderators: Stefano Mastrobuoni, MD, Ourania Preventza, MD & Bradley G. Leshnower, MD

10:30 AM - 10:37 AM

Management of Thoracic Aortic Disease Based on Underlying Gene Mutation
Josephina Meester, MD

10:37 AM - 10:44 AM

Managing Moderate to Severe Aortic Insufficiency at the Time of the Root Replacement - What is the role for valve repair in CTD?
Emmanuel Lansac, MD

10:44 AM - 10:51 AM

Fate of the Downstream Aorta after Root Replacement in CTD - Biomechanics and Aortic Stress Post Reconstruction
Elaine Tseng, MD

10:51 AM - 10:56 AM

Video Segment: VSRR in Patient with CTD and Mitral Regurgitation
Michael Chu, MD

10:56 AM - 11:06 AM

Panel Discussion

11:06 AM - 11:16 AM

6. Evaluation Of Peak Wall Stresses Across Tubingen Aortic Pathoanatomy (TAIPAN) Score For Aortic Diameter And Length In Ascending Thoracic Aortic Aneurysms
Siavash Zamirpour, Zhongjie Wang, Yue Xuan, Axel Gomez, Michael D. Hope, David Saloner, Julius Guccione, Liang Ge, Elaine E. Tseng.
University of California, San Francisco and San Francisco VA Medical Center, San Francisco, CA, USA.

Acute Aortic Dissection and Managing the Aortic Valve
Point Counter Point: Best Management of the Dilated Root in Acute Dissection in 50 year old patient

11:16 AM - 11:21 AM

VSRR Now Combined with Aortic Repair
Edward P. Chen, MD

11:21 AM - 11:26 AM

Limited Aortic Repair and Valve Resuspension Now, and Later VSRR
Ourania Preventza, MD

11:26 AM - 11:31 AM

Mechanical Bentall
Ourania Preventza, MD

11:31 AM - 11:36 AM

Bio-Bentall with Later TAVR
Susheel Kodali, MD

11:36 AM - 11:41 AM

Video Segment: Valve Resuspension and ArchFET/Antegrade Stenting in DeBakey1 Dissection with AI and Malperfusion
Maral Ouzounian, MD

11:41 AM - 11:50 AM

Discussion

11:50 AM - 12:00 PM

7. Outcomes Of Partial Aortic Root Replacement Approach In Acute Type A Aortic Dissection With Intimal Tear Extending To The Aortic Sinuses
Shi S. Poon, Pankaj Kumar.
Morriston Hospital, Swansea, United Kingdom.

12:00 PM - 1:00 PM

CONCURRENT INDUSTRY LUNCH

Lifetime Management of Aortic Valve Surgery
Moderators: Marta Sitges, MD & Vinod H. Thourani, MD

12:00 PM - 12:02 PM

Introductions and Welcome
Vinod H. Thourani, MD

12:02 PM - 12:12 PM

Differences in the European and U.S. Valve Guidelines
Marta Sitges, MD

12:12 PM - 12:22 PM

How I Decide on the First Valve Prosthesis in Patients between 60-65 years)
Jessica Forcillo, MD

12:22 PM - 12:32 PM

Potential Future Valve-in-Valve Technology
Mark Russo, MD

12:32 PM - 12:40 PM

TAVR Explant
Vinod H. Thourani, MD

12:40 PM - 12:59 PM

Panel Discussion

12:59 PM - 1:00 PM

Closing Remarks
Marta Sitges, MD

CME program supported by Edwards Lifesciences
Eden Roc 1A

Redefining Innovation in Valve Technology: Improved Anticoagulation vs. Reoperation
Program Description: The right valve for the right patient can lead to a long life well-lived, but the controversy in valve selection remains largely between improved anticoagulation and inevitable reoperation. Join us as we discuss how the PROACT studies with On-X are redefining innovation in valve technology � same valve, advancing indications.

Supported by Artivion
Eden Roc 1C

PLENARY SESSION II: TRICUSPID VALVE, THE NOT SO FORGOTTEN VALVE

1:00 PM - 2:30 PM

Chairs: Samir Kapadia, MD, & Mani Vannan, MD, Judy Hung, MD
Panelists: Kartik Sundareswaran, Bernard Zovighian, Pieter Kappetien & All Speakers

1:00 PM - 1:10 PM

Differences in Tricuspid Valve Regurgitation in the 2020 ACC/AHA and ESC/EACTS 2021 Guidelines
Patrick T. O'Gara, MD

1:10 PM - 1:20 PM

Role of Imaging for Indicating Interventions for TR
Rebecca T. Hahn, MD

1:20 PM - 1:30 PM

Surgical Tricuspid Valve Repair is the Gold Standard
Gilles D. Dreyfus, MD

1:30 PM - 1:40 PM

Timing of TV Surgery during MV Surgery
James Gammie, MD

1:40 PM - 1:50 PM

Discussion

1:50 PM - 2:00 PM

Transcatheter Edge to Edge Repair is the Procedure of Choice
Paul Sorajja, MD

2:00 PM - 2:10 PM

Transcatheter Replacement Provides the Best of Both Worlds
David Wood, MD

2:10 PM - 2:20 PM

Putting it all Together and Using my Crystal Ball: How will we be treating FTR in 2030, From Physiology to Patient Preference
Ralph Stephan von Baredelben, MD

2:20 PM - 2:30 PM

Discussion

2:30 PM - 3:00 PM

BREAK WITH INDUSTRY

Breakout Session 1 - Aortic Valve 2

3:00 PM - 5:00 PM

Lifetime Management of Aortic Stenosis
Moderators: Pinak Shah, MD, Vibhav Rangarajan, MD, & Kendra J. Grubb, MD

3:00 PM - 3:08 PM

Coronary Access after TAVR in Patients with Long Life-Expectancy
Lars Sondegaard, MD

3:08 PM - 3:16 PM

Commissural alignment: FAD or Critically needed?
Gilbert Tang, MD

3:16 PM - 3:24 PM

Discussion

Management of failed TAVR prosthesis in low-to-intermediate surgical risk patient

3:24 PM - 3:34 PM

8. Surgical Aortic Valve Replacement In Patients Aged 50-69 Years - Insights From The German Aortic Valve Registry (GARY)
Ferdinand A. Vogt¹, Giuseppe Santarpino², Buntaro Fujita³, Christian Frerke⁴, Timm Bauer⁵, Andreas Beckmann⁶, Raffi Bekeredjian⁷, Sabine Bleiziffer⁸, Helge M�llmann⁹, Thomas Walther¹⁰, Friedhelm Beyersdorf¹¹, Christian Hamm¹², Andreas Boening¹³, Stephan Baldus¹⁴, Stephan Ensminger³, Theodor Fischlein¹, Dennis Eckner¹⁵.
¹Department of Cardiac Surgery, Paracelsus Medical University Nuremberg, Nuremberg, Germany, ²Paracelsus Medical University Nuremberg, N�rnberg, Germany, ³Department of Thoracic and Cardiovascular Surgery, University Hospital, L�beck, L�beck, Germany, ⁴Department of Cardiology, University Hospital, Heart Center, L�beck, L�beck, Germany, ⁵Department of Cardiology, Sana Klinikum Offenbach, Offenbach, Germany, ⁶ German Society of Thoracic, Cardiac and Vascular Surgery (Deutsche Gesellschaft f�r Thorax-, Herz- und Gef��chirurgie, DGTHG), Berlin, Berlin, Germany, ⁷ Department of Cardiology, University of Heidelberg, Heidelberg, Germany, ⁸Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, Ruhr-University Bochum, Bad Oeynhausen, Bad Oeyenhausen, Germany, ⁹Department of Internal Medicine I, St.-Johannes-Hospital, Dortmund, Dortmund, Germany, ¹⁰Department of Cardiac, Thoracic and Thoracic Vascular Surgery, University Hospital Frankfurt, Frankfurt, Germany, ¹¹Department of Cardiovascular Surgery, Heart Centre Freiburg University, Freiburg, Germany, ¹²Kerckhoff Heart and Thorax Center, Bad Nauheim, Kerckhoff Campus of Justus-Liebig University, Giessen, Giessen, Germany, ¹³Department of Cardiothoracic Surgery, University Hospital Giessen, Giessen, Germany, ¹⁴Department of Internal Medicine III, University Hospital of Cologne, Cologne, Germany, ¹⁵Department of Cardiology, Paracelsus Medical University Nuremberg, Nuremberg, Germany.

3:34 PM - 3:44 PM

9. Prosthetic Valve Leaflet Resection Under Direct Vision To Avoid Coronary Obstruction And Facilitate Both Viv Tavr And Tav-in-tav
Keith Allen, Adnan Chhatriwalla, John Saxon, Russell Davis, Michael Gibson, Chetan Huded, Anthony Hart.
St. Luke's Mid America Heart Institute, Kansas City, MO, USA.

3:44 PM - 3:49 PM

Case Presentation: Management of failed TAVR prosthesis in low-to-intermediate surgical risk patient
Merryking Neville, MD

3:49 PM - 3:57 PM

TAVR Explant
Vinod H. Thourani, MD

3:57 PM - 4:15 PM

Discussion

4:15 PM - 4:25 PM

10. Transcatheter Aortic Valve Leaflet Characteristics Influence Neo-Sinus Geometry And Leaflet Thrombosis Potential
Beatrice E. Ncho, Ph.D, Vahid Sadri, Ph.D, Andrew W. Siefert, Ph.D, Ajit P. Yoganathan, Ph.D.
Georgia Institute of Technology, ATLANTA, GA, USA.

Management of failed SAVR Bioprosthesis

4:25 PM - 4:30 PM

Case Presentation
Mei Chau, MD

4:30 PM - 4:38 PM

When is Valve-in-Valve the best choice?
Janarthanan Sathananathan, MD

4:38 PM - 4:46 PM

When is redo-SAVR the best choice?
Mortiz von Ballmoos, MD, PhD

4:46 PM - 5:00 PM

Discussion

Breakout Session 2 - Atrial Fib 1

3:00 PM - 5:00 PM

Moderators: Marc Gillinov, MD & Sandeep Goyal, MD

3:00 PM - 3:08 PM

Catheter Ablation of Atrial Fibrillation
Sandeep Goyal, MD

3:08 PM - 3:16 PM

Hybrid Surgical Ablation
Christian Shutls, MD

3:16 PM - 3:24 PM

Choosing a Surgical Lesion Set for Concomitant Surgical Ablation
V. Seenu Reddy, MD

3:24 PM - 3:42 PM

Discussion

3:42 PM - 3:52 PM

11. Patients With Atrial Fibrillation Benefit From SAVR With Surgical Ablation Compared To TAVR Alone
William L. Patrick, Zehang Chen, Joseph E. Bavaria, Jason J. Han, Benjamin Smood, Akhil Rao, Fabliha Khurshan, Siddharth Yarlagadda, Amit Iyengar, John J. Kelly, Joshua C. Grimm, Marisa Cevasco, Nimesh D. Desai.
University of Pennsylvania, Philadelphia, PA, USA.

3:52 PM - 4:00 PM

Stroke Prevention in Afib
Kevin Makati, MD

4:00 PM - 4:08 PM

LAA Percutaneous Management
Sandeep Goyal, MD

4:08 PM - 4:16 PM

LAA Surgical Management
Mark Gillinov, MD

4:16 PM - 4:26 PM

Discussion

4:26 PM - 4:34 PM

New Technologies in Atrial Fibrillation Management
Kevin Makati, MD

4:34 PM - 4:42 PM

Predictors for Recurrence of Atrial Fibrillation Following Surgical and Transcatheter Intervention
Michael Hoosien, MD

4:42 PM - 5:00 PM

Discussion

Breakout Session 3 - Tricuspid Valve 1

3:00 PM - 5:00 PM

Challenging Tricuspid Entities: Endocarditis, Degenerative, Rheumatic, and Latrogenic Lesions
Moderators: Marta Sitges, MD & Steven F. Bolling, MD

3:00 PM - 3:10 PM

Introduction by Moderators

3:10 PM - 3:18 PM

Imaging Classification and Characteristics of Degenerative TV Disease
Rebecca T. Hahn, MD

3:18 PM - 3:26 PM

The Growing Problem with Iatrogenic Lesions in Tricuspid Regurgitation
Judy Hung, MD

3:26 PM - 3:34 PM

Tricuspid Valve Geometry and dynamics after Annuloplasty
Manuel Rausch, MD

3:34 PM - 3:42 PM

Tricuspid Valve Repair for Rheumatic Disease
Bashi Velayudhan, MD

3:42 PM - 3:52 PM

Discussion

3:52 PM - 4:00 PM

Principles of Surgical Therapy for Endocarditis
Stefano Matrobuoni, MD

4:00 PM - 4:08 PM

Recurrence in Tricuspid Endocarditis: When and How to Operate
T. Sloane Guy, MD

4:08 PM - 4:16 PM

Understanding the Physiology of the Right Ventricle with severe FTR
Tomasz A. Timek, MD

4:16 PM - 4:50 PM

Discussion

4:50 PM - 5:00 PM

12. WITHDRAWN

Breakout Session 4 - Abstract Session Basic Science

3:00 PM - 5:00 PM

Moderators: Murali Padala, MD & Russell Norris, MD

3:00 PM - 3:12 PM

13. Sex-related Signalling Of Aldosterone/mineralocorticoid Receptor Pathway In Calcific Aortic Stenosis
Lara Matilla Cuenca¹, Rafael Sadaba¹, Eva Jover¹, Mattie Garaikoetxea¹, Vanessa Arrieta¹, Amaia Garcia-Pe�a¹, Adela Navarro¹, Amaya Fernandez-Celis¹, Alicia Gainza¹, Virginia �lvarez¹, Frederic Jaisser², Natalia L�pez-Andr�s¹.
¹Navarrabiomed, Pamplona, Spain, ²Centre de Recherche des Cordeliers, Sorbonne Universite?, Inserm, Universite? de Paris, Team Diabetes, metabolic diseases and comorbidities, F-⁷⁵⁰⁰⁶, Paris, France.

3:12 PM - 3:24 PM

14. Simulating The 3d Contractile Function Of The Aortic Heart Valve Interstitial Cell
Alex Khang¹, John Steinman¹, Xinzeng Feng¹, Chiara Camillo², Giovanni Ferrari², Michael S. Sacks¹.
¹The University of Texas at Austin, Austin, TX, USA, ²Columbia University, New York City, NY, USA.

3:24 PM - 3:36 PM

15. Low Dose Galunisertib Halts Aortic Stenosis Progression By Inhibiting TGF-? Signaling In Mice
Kumar Subramani, Sandeep Subrahmanian, Rohan Varshney, Thamizhiniyan Venkatesan, Brienne Cortez, Pratibha Dube, Jasimuddin Ahamed.
Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

3:36 PM - 3:48 PM

16. Structure-Function-Molecular Relationships Of The Extracellular Matrix Of Aortic Valves In Mouse Models Of Human Disease
Kaitlyn Thatcher¹, Carol Mattern¹, Jessica Fulton², Felix Liu³, Michael McDermott⁴, Cristopher Breuer³, Brian Hoffmann⁵, Joy Lincoln¹.
¹Medical College of Wisconsin, Wauwatosa, WI, USA, ²Center for Cardiovascular Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA, ³Center for Regenerative Medicine, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA, ⁴Center for Cardiovascular Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA, ⁵The Jackson Laboratory, Bar Harbor, ME, USA.

3:48 PM - 4:00 PM

17. Immune Response As A New Player In Mitral Valve Prolapse
Constance Delwarde¹, Pascal Aumond¹, Claire Toquet², amir h kayvanjoo³, Elvira Mass³, benjamin lauzier¹, severine remy⁴, Ignacio Anegon⁴, Jean-Jacques Schott¹, Thierry Le Tourneau², jean M�rot¹, romain capoulade¹.
¹Nantes Univ, CNRS, INSERM, thorax institute, Nantes, France, ²Nantes Univ, CHU Nantes, CNRS, INSERM, thorax institute, Nantes, France, ³Life and Medical Sciences Institute, Bonn, Bonn, Germany, ⁴Transgenic Rats Immunophenomic, Nantes, France.

4:00 PM - 4:12 PM

18. Mechanisms Of Regionalized Left Ventricular Fibrosis In Mitral Valve Prolapse
Jordan Ellis Morningstar¹, Cortney Gensemer¹, Tyler Beck¹, Ayesha Vohra¹, Diana Fulmer¹, Christina Wang¹, Kelsey Moore¹, Natalie Koren¹, Lilong Guo¹, Reece Moore¹, Franz Sieg², Yasufumi Nagata³, Philippe Bertrand⁴, Ricardo Spampinato², Janiece Glover¹, William Richardson⁵, Robert A. Levine³, Michael Borger², Russell Norris¹.
¹Medical University of South Carolina, Charleston, SC, USA, ²Leipzig Heart Institute, Leipzig, Germany, ³Massachusetts General Hospital, Boston, MA, USA, ⁴Massachusetts general hospital, Boston, MA, USA, ⁵Clemson University, Clemson, SC, USA.

4:12 PM - 4:24 PM

19. Mitral Valve Prolapse: A Tissue Engineering Model
Collin Owens, Agneta Simionescu.
Clemson University, Clemson, SC, USA.

4:24 PM - 4:36 PM

20. Dzip1 Regulates Mammalian Cardiac Valve Development Through A Cby1-b Catenin Mechanism
Lilong Guo, Tyler Beck, Cortney Gensemer, Jordan Morningstar, Richel Biggs, Natalie Koren.
Medical University of South Carolina, CHARLESTON, SC, USA.

4:36 PM - 4:48 PM

21. Ltbp2 Mutation May Cause Mitral Valve Prolapse
Shoshi Shpitzen, Idit Tesler, Dan Gilon, Donna Zwas, David Leibowitz, Ronen Durst.
Hadassah Medical Center, Jerusalem, Israel.

4:48 PM - 5:00 PM

22. Remodeling Of Valvular Interstitial Cells Under Diabetic Treatment Is Mediated By MTOR Signaling
Jessica I. Selig¹, Hannah Viviana Krug¹, Felix Kraft¹, Elena Adler¹, D. Margriet Ouwens², Artur Lichtenberg¹, Payam Akhyari¹, Mareike Barth¹.
¹Department of Cardiac Surgery, Medical Faculty and University Hospital D�sseldorf, Heinrich-Heine-University D�sseldorf, D�sseldorf, Germany, ²Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), D�sseldorf, Germany.

5:00 PM - 6:30 PM

POSTER COMPETION & RECEPTION

FRIDAY, 4 MARCH 2022

7:00 AM - 7:50 AM

BREAKFAST WITH INDUSTRY

Breakout Session 1 - Aortic Valve 3 and Proximal Aorta

8:00 AM - 10:00 AM

Aortic Valve and Proximal Aorta
Moderators: Jessica Forcillo, MD, V. Seenu Reddy, MD, & Vinod H. Thourani, MD

8:00 AM - 8:08 AM

Patient Selection and Shared Decision Making in patients with BAV and Aortopathy
Hanneke Takkenberg, MD

8:08 AM - 8:16 AM

Genetics on Bicuspid Aortic Valve - Recent Updates
Elana Aikawa, MD, PhD

8:16 AM - 8:24 AM

Bicuspid Aortic Valve Morphology and Outcomes after TAVR
Vaikom Mahadevan, MD

8:24 AM - 8:34 AM

Discussion

8:34 AM - 8:44 AM

23. Male-female Differences In The Natural History Of Ascending Thoracic Aortic Aneurysms: The DisSEXion Study
Maximiliaan L. Notenboom, BSc¹, Arjen G�kalp, MD¹, Kevin M. Veen, PhD¹>, Roland van Kimmenade, MD, PhD², Guillaume Geuzebroek, MD, PhD², Michel Verkroost, MD, PhD², Jolien W. Roos-Hesselink, MD, PhD¹, Ad J.J.C. Bogers, MD, PhD¹, Johanna J.M. Takkenberg, MD, PhD¹.
¹Erasmus University Medical Center, Rotterdam, Netherlands, ²Radboud University Medical Center, Nijmegen, Netherlands.

Case-Based Discussion with Expert Panelists

8:44 AM - 8:52 AM

25-Year-Old with UAV-AI (without aortopathy?): Timing of intervention, type of intervention
Chris Malaisrie, MD

8:52 AM - 9:00 AM

40 years old with isolated BAV AI with Normal Root and Ascending Aorta
John Elefteriades, MD

9:00 AM - 9:08 AM

45 Year Old with UAV AS/AI with Ascending Aneurysm / 39mm Root - type of intervention, Ascending/AVR vs Bentall vs Ross
Stefano Mastrobuoni, MD

9:08 AM - 9:16 AM

55y/o with BAV Isolated AS - type of Valve Mechanical (one and done), stented bioprosthetic (later TAVR), stentless bioprosthetic (is later TAVR an option), Ross (can it be one and done), TAVR 1st / SAVR or TAVR2 later?
Basel Ramlawi, MD

Video session on the treatment of BAV/AR

9:15 AM - 9:22 AM

Surgical Video of VSRR for bicuspid AV and AR
Hans Schafers, MD

9:22 AM - 9:29 AM

Surgical Video BAV / AR Ross + Anuloplasty and STJ Stabilization
Ismail El Hamamsy, MD, PhD

9:29 AM - 9:36 AM

Transcatheter Treatment of AR
Torsten Vahl, MD

9:36 AM - 9:43 AM

Discussion

SAVR vs TAVR in BAV- What would I want if I were a 64yo with AS, calcified raphe, and an ascending of 4.5cm?

9:43 AM - 9:48 AM

SAVR
Susheel Kodali, MD

9:48 AM - 9:53 AM

TAVR
Yoshi Kaneko, MD

9:53 AM - 10:00 AM

Discussion

Breakout Session 2 - Mitral Valve 2

8:00 AM - 10:00 AM

Modern Concepts in Secondary Mitral Regurgitation
Moderator: Marc Gillinov, MD & Murali Padala, PhD

8:00 AM - 8:08 AM

Ventricular Remodeling and Anatomic Considerations in Treating Secondary MR
Murali Padala, PhD

8:08 AM - 8:16 AM

A Novel Anchoring System TMVR and Beyond
Vivek Rajagopal, MD

8:16 AM - 8:24 AM

Can imaging identify which patients should have which therapy?
Nadira Hamid, MD

8:24 AM - 8:32 AM

Disproportionate MR, Is There Actual Physiological Data?
Kostantinos Koulogiannis, MD

8:32 AM - 8:40 AM

How to Maximize Medical Therapy and CRT In Patients with Secondary MR as a Means of Preventing Intervention
Robert Cole, MD

8:40 AM - 8:50 AM

Discussion

8:50 AM - 8:58 AM

Intervening on Functional MR- Who? When? Why?
Marco Di Eusanio, MD

8:58 AM - 9:06 AM

The Role for Surgery in the Management of Ischemic MR
Isaac George, MD

9:06 AM - 9:14 AM

Transcatheter Repair Technologies for Ischemic MR
Martin Andreas, MD

9:14 AM - 9:22 AM

Transcatheter Replacement Technologies for Ischemic MR
Pradeep Yadav, MD

9:22 AM - 9:40 AM

Panel Discussion

9:40 AM - 9:50 AM

24. Transcatheter Mitral Valve Profile Impacts Left Ventricular Outflow Tract Hemodynamics: An In Silico Study
Keshav Kohli¹, Yinghan Xu¹, Zhenglun Alan Wei¹, Tiffany Netto¹, Adam Greenbaum², Vasilis Babaliaros², Philipp Blanke³, John Oshinski², Ajit Yoganathan¹.
¹ Georgia Institute of Technology, Atlanta, GA, USA, ²Emory University, Atlanta, GA, USA, ³St. Paul's Hospital & University of British Columbia, Vancouver, BC, Canada.

9:50 AM - 10:00 AM

25. A Leaflet Enhancing Implant To Treat Functional Mitral Regurgitation: In-vitro And In-vivo Efficacy Studies
Kirthana Sreerangathama Suresh¹, Dongyang Xu¹, Daisuke Onohara¹, Takanori Kono², Qi He¹, Michael Silverman¹, Muralidhar Padala¹.
¹Emory University, Atlanta, GA, USA, ²Kurume University, Fukuoka, Japan.

Breakout Session 3 - N/A

Breakout Session 4 - Abstract Session 2: Miscellaneous

8:00 AM - 10:00 AM

Moderators: Pradeep Dasi, MD & Elaine E. Tseng, MD

8:00 AM - 8:12 AM

26. Non-invasive Detection Of Reduced Leaflet Motion In Transcatheter Aortic Valves Via Embedded Wireless Pressure Microsensors - An In-silico Proof-of-concept
Shantanu Bailoor¹, Jung Hee Seo¹, Lakshmi P. Dasi², Stefano Schena³, Rajat Mittal¹.
¹Johns Hopkins University, Baltimore, MD, USA, ²Georgia Institute of Technology, Atlanta, GA, USA, ³Johns Hopkins Medical Institute, Baltimore, MD, USA.

8:12 AM - 8:24 AM

27. Impact Of Blood Pressure Conditions On Coronary Perfusion And Hemodynamics After Aortic Valve Replacement
Brennan Vogl¹, Scott Lilly², Vinod Thourani³, Mohamad Alkhouli⁴, Brian Lindman⁵, Hoda Hatoum¹.
¹Biomedical Engineering Department, Michigan Technological University, Houghton, MI, USA, ²Department of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA, ³Department of Cardiovascular Surgery, Piedmont Heart Institute, Atlanta, GA, USA, ⁴Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA, ⁵Department of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.

8:24 AM - 8:36 AM

28. Shear-induced Thrombogenic Potential Of A Novel Tri-leaflet Mechanical Heart Valve Prosthesis Compared To A Bioprosthetic Valve And A Bi-leaflet Mechanical Valve: In-vitro Study Of Complex Flow Patterns And Turbulence
Leonardo Pietrasanta, Dominik Obrist.
University of Bern, Bern, Switzerland.

8:36 AM - 8:48 AM

29. Study Of The Flutter Kinematics And Blood Flow Motion For Bioprosthetic Aortic Valves With Different Designs
Pascal Corso¹, Fergal B. Coulter², Maria G. Ch. Nestola³, Silje E. Jahren¹, Dominik Obrist¹.
¹University of Bern, Bern, Switzerland, ²ETH Zurich, Zurich, Switzerland, ³Universit� della Svizzera italiana, Lugano, Switzerland.

8:48 AM - 9:00 AM

30. Changes In The In Vivo Functional State Of The Mitral Valve In Edge-to-edge Leaflet Approximation
Natalie Simonian¹, Joseph H. Gorman, III², Robert C. Gorman², Sneha Vakamudi³, Mark J. Pirwitz³, Michael S. Sacks¹.
¹University of Texas at Austin, Austin, TX, USA, ²University of Pennsylvania, Philadelphia, PA, USA, ³Ascension Texas Cardiovascular, Austin, TX, USA

9:00 AM - 9:12 AM

31. Transcatheter Versus Surgical Pulmonary Valve Replacement: A Side-by-side Structural And Hemodynamic Characterization
Mina Shafiei, Dong Qiu, Ali Azadani.
University of Denver, Denver, CO, USA.

9:12 AM - 9:24 AM

32. The Impact Of Coaptation Reserve In Mitral Regurgitation With Transcatheter Edge-to-edge Repair
Hirotomo Sato, Joao Cavalcante, Richard Bae, Vinayak Bapat, Santiago Garcia, Mario Goessl, Go Hashimoto, Miho Fukui, Maurice Enriquez-Sarano, Paul Sorajja.
Minneapolis Heart Institute Foundation, Minneapolis, MN, USA.

9:24 AM - 9:36 AM

33. Porcine Vs. Bovine Pericardium Assessment As A Leaflet In Aortic Valves
Nazanin Afsar Kazerooni, Ekaterina Tkatchouk.
Edwards Lifesciences, Irvine, CA, USA.

9:36 AM - 9:48 AM

34. Annuloplasty Ring Suture Forces Differ By Ring Type In An IMR Diseased Ovine Model
Sanchita S. Bhat¹, Katelynne Berland¹, Andrew W. Siefert¹, Maeve Janecka¹, Shelley Chee-Mei Gooden¹, Beatrice E. Ncho¹, Takayuki Kawashima², Mori Kazuki², Satoshi Kozaki², Robert C. Gorman², Joseph H. Gorman, III², Ajit Yoganathan¹.
¹Georgia Institute of Technology, Atlanta, GA, USA, ²University of Pennsylvania, Philadelphia, PA, USA.

9:48 AM - 10:00 AM

35. Splitting The Anterior Mitral Leaflet Impairs Left Ventricular Function In An Ovine Model
Laurencie M. Brunel¹, Zoe A. Williams¹, Konstantin Yastrebov², Benjamin M. Robinson¹, Innes K. Wise¹, Hugh S. Paterson¹, Christopher S. Burrows¹, Paul G. Bannon¹.
¹The University of Sydney, Sydney, Australia, ²The University of New South Wales, Sydney, Australia.

10:00 AM - 10:30 AM

BREAK WITH INDUSTRY

PLENARY SESSION III: PRESIDENTIAL ADDRESS

10:30 AM - 12:00 PM

Moderators: Marta Sitges, MD & Vinod H. Thourani, MD

10:30 AM - 10:45 AM

Business Meeting

10:45 AM - 11:05 AM

Honoring of the HVS Past Presidents
Introduced by: Vinod H. Thourani, MD

11:05 AM - 11:25 AM

Keynote: "Bring the world together: ICHOM standard for HVD patient outcomes"
Emmanuel Lansac, MD & Hanneke Takkenburg, MD, PhD

11:25 AM - 11:30 AM

Inaugural HVS Lifetime Achievement Award
Ajit Yoganathan, PhD

Introduced by: Vinod H. Thourani, MD

11:30 AM - 11:35 AM

Introduction of the President
Marta Sitges, MD

11:35 AM - 12:00 PM

Presidential Address
"The marriage of innovation and improving quality"
Vinod H. Thourani, MD

12:00 PM - 1:00 PM

CONCURRENT INDUSTRY LUNCH
Contemporary and future treatment of mitral valve disease - a case-based discussion
Introductions - Pieter Kappetein, M.D.

"Mitral valve decision-making in 2022 - repair or replace?"
Rob Smith, M.D.

"Mitral valve decision-making in 2022 - ring or band?"
Gorav Ailawadi, M.D.

"Future options for mitral valve patients - an update on the Apollo trial"
Michael Mack, M.D.

Discussion/Q&A � all faculty

Supported by Medtronic
Eden Roc 1A

Broadening Your Repertoire in the Management of Mitral Valvular Disease
Moderator: Vinod H. Thourani, MD

12:00 PM - 12:05 PM

Introductions and Welcome
Vinod H. Thourani, MD

12:05 PM - 12:20 PM

New Technology in Mitral Valve Replacement
Mark Russo, MD

12:20 PM - 12:35 PM

TEER is the New Gold Standard for Functional MR
Pradeep Yadav, MD

12:35 PM - 12:50 PM

Performing Mitral valve in valve: Is redo-MVR obsolete?
Yoshi Kaneko, MD

12:50pm � 12:59pm

Panel Discussion

Supported by Abbott
Eden Roc IB

Surgical LAA Exclusion: State-of-the-Art
This CME accredited symposium will review the results the LAAOS III trial and assess impact to the practice of surgical LAA exclusion. Additional lectures will examine the necessity of OAC for patients discharged in sinus rhythm after Cox Maze IV procedure, and evaluate standalone epicardial LAA exclusion for thromboembolism prevention in AF, as well as prophylactic epicardial LAA exclusion for thromboembolism prevention in high-risk patients.

Supported by Atricure
Eden Roc 1C

Breakout Session 1 - Creating Research Databases for Quality Assessment and Research

1:00 PM - 2:30 PM

Moderators: Jeffrey P. Jacobs, MD, & Nimesh Desai, MD

1:00 PM - 1:08 PM

The updated STS Adult Cardiac Database: new and improved features - now and the future
Jeffrey P. Jacobs, MD

1:08 PM - 1:16 PM

The EACTS Adult Cardiac Databsase
Chris Bond, MD

1:16 PM - 1:24 PM

ASCVTS Cardiac Surgery Database
Noboru Motomura, MD, PhD

1:24 PM - 1:44 PM

Discussion

1:44 PM - 1:52 PM

The HVS Aortic Valve Research Network
Philippe Pibarot, DVM

1:52 PM - 2:00 PM

The STS-ACC TVT Registry: Multispecialty Collaboration with Transformative Technology
Vinod H. Thourani, MD

2:00 PM - 2:08 PM

The STS Congenital Database
Jeffrey P. Jacobs, MD

2:08 PM - 2:16 PM

The STS INTERMACS Registry
Ezequiel Molina, MD

2:16 PM - 2:30 PM

Discussion

Breakout Session 2 - Mitral Valve 3

1:00 PM - 2:30 PM

Future Considerations for Degenerative Mitral Regurgitation
Moderators: Gorav Ailawadi, MD, Kimberly Atianzar, MD, & Juan P. Umana, MD

1:00 PM - 1:08 PM

Predicting Procedural Success by Imaging: Let me let you know if you should Repair or Replace the MV
Zuyue Wang, MD

1:08 PM - 1:16 PM

Future Surgical Therapies: What will we be doing?
Gorav Ailawadi, MD

1:16 PM -1:24 PM

Future Transcatheter Therapies: What will we be doing?
Rahul Sharma, MD

1:24 PM - 1:32 PM

Why is Transcatheter Mitral Replacement Taking Longer Than TAVR for Success?
Tom C. Nguyen, MD

1:32 PM - 1:42 PM

Discussion

Case Presentations: Contrasting Surgery and Transcatheter Techniques

1:42 PM - 1:47 PM

Surgical Therapy Barlow's MV
Rakesh Suri, MD

1:47 PM - 1:52 PM

Transcatheter Therapy for Barlow's MV
Philippe Genereux, MD

1:52 PM - 1:57 PM

Discussion

1:57 PM - 2:02 PM

Anterior Flail/Commissural Prolapsed MV
Surgical Therapy for Anterior Flail Prolapsed MV
T. Sloane Guy, MD

2:02 PM - 2:07 PM

Transcatheter Therapy for Anterior Flail Prolapse
Andrew Morse, MD

2:07 PM - 2:12 PM

Discussion

2:12 PM - 2:17 PM

Transapical Repair of the MV with No Annuloplasty Ring
Frederico Milla, MD

2:17 PM - 2:20 PM

Discussion

2:20 PM - 2:30 PM

36. Effect Of Neo-chord Angulation On Chordal Force During Mitral Valve Prolapse Repair: An In Vitro Study
Vahid Sadri¹, Keshav Kohli¹, Jorge H Jimenez¹, William S Cranford¹, Abigail R Berry¹, Daniel Grinberg², W Randolph Chitwood³, Ajit P Yoganathan¹.
¹Georgia Institute of Technology, Atlanta, GA, USA, ²H�pital Louis Pradel, Lyon, France, ³East Carolina University, Greenville, NC, USA.

Breakout Session 3 - Tricuspid Valve 2

1:00 PM - 2:30 PM

Solutions for Tricuspid Regurgitation
Moderators: Brian R. Lindman, MD, Sara Mobasseri, MD, & Brian Bethea, MD

1:00 PM - 1:10 PM

37. Right Ventricular Papillary Muscle Approximation Is An Effective Surgical Repair For Functional Tricuspid Regurgitation
Dongyang Xu, Daisuke Onohara, Kirthana Sreerangathama Suresh, Qi He, Muralidhar Padala.
Emory University, Atlanta, GA, USA.

1:10 PM - 1:18 PM

The Need for Solutions in TR
Brian R. Lindman, MD

1:18 PM - 1:26 PM

Choosing the Right Thresholds for Therapy
Joao Cavalcante, MD

1:26 PM - 1:34 PM

Minimally Invasive Endoscopic Tricuspid Repair
Rodrigo De Souza, MD

1:34 PM - 1:44 PM

Discussion

1:44 PM - 1:52 PM

Why Transcatheter Solutions Will and Will Not Work
Maurizio Taramasso, MD

1:52 PM - 2:00 PM

Biomatrix Tricuspid Valve - Getting to a New Normal
Marc Gerdisch, MD

2:00 PM - 2:08 PM

Will Surgery Remain the Gold Standard for TR?
Ourania Preventza, MD

2:08 PM - 2:30 PM

Panel Discussion

Breakout Session 4 - Abstract Session 3 - Translational

1:00 PM - 2:30 PM

Moderators: Hanneke Takkenberg, MD & Jessica Forcillo, MD

1:00 PM - 1:12 PM

38. Restoration Of Endogenous Tissue In 4yr Explant Of The Xeltis PV Conduit: Promising Results
David L. Morales¹, Zsolt Prod�n², Gerardus Bennink³, Renu Virmani⁴.
¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA, ²Gottsegen Gy�rgy Hungarian Institute of Cardiology, Budapest, Hungary, ³Heart Center of the University of Cologne, Cologne, Germany, ⁴CVPath Institute, Gaithersburg, MD, USA.

1:12 PM - 1:24 PM

39. Computational Analysis Of The Effects Of Papillary Muscle Approximation On Mitral Valve Leaflet Stresses In The Repair Of Functional Mitral Regurgitation
Gediminas Gaidulis, Muralidhar Padala.
Emory University, Atlanta, GA, USA.

1:24 PM - 1:36 PM

40. 4D Echocardiographic Estimation Of Aortic Root Strain In Trileaflet And Bicuspid Aortic Valves
Ankush Aggarwal¹, Peter Mortensen¹, Jilei Hao², Lukasz Kaczmarczyk¹, Albert T. Cheung³, Lourdes Al Ghofaily², Robert C. Gorman², Nimesh D. Desai², Joseph E. Bavaria², Alison M. Pouch².
¹University of Glasgow, Glasgow, United Kingdom, ²University of Pennsylvania, Philadelphia, PA, USA, ³Stanford University, Stanford, CA, USA.

1:36 PM - 1:48 PM

41. Incidence And Clinical Impact Of Patient-Prosthesis Mismatch After Rapid-Deployment Aortic Valve Replacement
Giorgia Cibin, Augusto D'Onofrio, Valentina Lombardi, Emma Bergonzoni, Chiara Tessari, Gino Gerosa.
University of Padova, Padova, Italy.

1:48 PM - 2:00 PM

42. Complex Minimal Invasive Mitral Valve Repair In Patients With Single Or Bi-leaflet Prolapse: Loop Versus Non-loop Reconstruction
Marie-Elisabeth Stelzmueller, Guenther Laufer, Wilfried Wisser, MD.
Medical University Vienna, Vienna, Austria.

2:00 PM - 2:12 PM

43. In-vivo Model Of Bioscaffold Mitral Valve Replacement In The Juvenile Non-human Primate.
Steven Bibevski¹, Brittany Gonzalez², Sharan Ramaswamy², Frank Scholl¹.
¹Joe DiMaggio Children's Hospital, Hollywood, FL, USA, ²Florida International University, Miami, FL, USA.

2:12 PM - 2:24 PM

44. Patients Younger Than 60 Years With Bioprosthetic Surgical Aortic Valve Replacement
Ruggero de Paulis¹, Thomas Senage², Michael A. Borger³, Matthias Siepe⁴, Pierluigi Stefano⁵, Guenther Laufer⁶, Thierry Langanay⁷, Bart Meuris⁸.
¹European Hospital, Rome, Italy, ²CHU Nantes, Nantes, France, ³Leipzig Heart Center, Leipzig, Germany, ⁴Heart Center University of Freiburg, Freiburg, Germany, ⁵Careggi University Hospital, Florence, Italy, ⁶Medical University Wien, Vienna, Austria, ⁷Rennes University Hospital Center, Rennes, France, ⁸UZ Leuven, Leuven, Belgium.

2:30 PM - 3:00 PM

BREAK WITH INDUSTRY

PLENARY SESSION IV: AORTIC, THE STORY HAS JUST BEGUN

3:00 PM - 5:00 PM

Chairs: Hanneke Takkenburg, MD, PhD, & Maurice Sarano, MD
Panelists: Larry Wood (Edwards), Samuel Conaway (Boston Scientific)

3:00 PM - 3:10 PM

What's new on the Aortic Valve in the 2020 ACC/AHA and ESC/EACTS 2021 Guidelines
Hanneke Takkenberg, MD, PhD

3:10 PM - 3:20 PM

Discussion

3:20 PM - 3:30 PM

Should Moderate Aortic Stenosis with Symptoms be Treated with Valve Replacement?
Philippe Genereux, MD

3:30 PM - 3:40 PM

Biochemical Testing should be Guiding our Management of AS
Brian R. Lindman, MD

3:40 PM - 3:50 PM

Discussion

3:50 PM - 4:12 PM

TAVR for All Low Risk Patients with Good TAVR Imaging Anatomy, Regardless of the Age?
Pro: Bernard Pendergast, MD
Con: George Dangas, MD

4:12 PM - 4:24 PM

TAVR Valve-in-valve vs. Redo SAVR for Low-intermediate Risk Patients:
Pro-TAVR: Hasan Jilailhawi, MD
Pro-SAVR: Michael J. Reardon, MD

4:24 PM - 4:32 PM

Shared Decision Making in Treatment Aortic Stenosis: From the Mechanical Surgical Prosthesis to TAVR
Roxana Mehran, MD

4:32 PM - 4:45 PM

Discussion

4:45 PM - 5:00 PM

Putting it all Together and Using my Crystal Ball: How will we be treating AV Disease in 2030, From Physiology to Patient Preference
Martin Leon, MD

5:00 PM - 6:00 PM

Attendee Reception & Poster Winner Announcement

SATURDAY, 5 MARCH 2022

7:30 AM � 8:30 AM

CONTINENTAL BREAKFAST

Breakout Session 1 - Aortic Valve 4

8:30 AM - 10:00 AM

Patient Prosthesis Mismatch and Durability
Moderators: Amr Abbas, MD & Peter Flueckiger, MD

8:30 AM - 8:38 AM

Challenges in the Assessment of Valve Hemodynamics Following AVR: Echo vs. Invasive Measurements
Amr Abbas, MD

8:38 AM - 8:46 AM

Definition, Diagnosis, and Incidence of Patient Prosthesis Mismatch following TAVR vs. SAVR
Julien Ternacle, MD

8:46 AM - 8:54 AM

Prosthesis-Patient Mismatch: Impact on Outcomes following TAVR and SAVR
Rebecca T. Hahn, MD

8:54 AM - 9:04 AM

Discussion

9:04 AM - 9:14 AM

45. Edwards Inspiris Resilia�Prosthesis For Aortic Valve Replacement In Young Adults: Short-term And Mid-term Clinical Outcome And Haemodynamic Performances
Alessandra Francica, FIippo Tonelli, Cecilia Rossetti, Ilaria Tropea, Luciana Benvegn�, Giovanni Battista Luciani, Giuseppe Faggian, Francesco Onorati
University of Verona Medical School, Verona, Italy.

9:14 AM - 9:24 AM

46. Patient-prosthesis Mismatch Rates In Magna Ease Versus Trifecta Bioprosthetic Aortic Valves: Analysis Of Single-center Surgical Data
Aurinjoy Gupta, BSc¹, Hashem Aliter, MD², Chris Theriault, Prof Eng³ Edgar Chedrawy, MD².
¹Northern Ontario School of Medicine, Thunder Bay, ON, Canada, ² Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada, ³ Research Methods Unit, Nova Scotia Health Authority, Halifax, NS, Canada.

9:24 AM - 9:32 AM

Gender Differences in PPM following TAVR or SAVR
Elaine E. Tseng, MD

9:32 AM - 9:40 AM

Understanding Structural Valve Deterioration and Failure following AVR: VARC 3 Definitions
Philippe Pibarot, DVM

9:40 AM - 9:48 AM

Valve Durability in TAVR vs. SAVR
H�l�ne Eltchaninoff, MD

9:48 AM - 10:00 AM

Discussion

Breakout Session 2 - Mitral Valve 4

8:30 AM - 10:00 AM

Mitral Annular Calcification
Moderators: Amy Simone, PA & Kostantinos Koulogiannis, MD

8:30 AM - 8:38 AM

Acquired and Degenerative Mitral Stenosis: Similarities and Differences in Presentation and Outcomes
Kostantinos Koulogiannis, MD

8:38 AM - 8:46 AM

Risk Factors Associated with the Incidence and Progression of Mitral Annulus Calcification: the Multi-Ethnic Study of Atherosclerosis
Sammy Elmariah, MD

8:46 AM - 8:54 AM

Understanding Disease Activity in Mitral Annular Calcification with Imaging
Prasad Dasi, MD

8:54 AM - 9:02 AM

Multimodality Imaging for Therapeutic Strategies and Interventions in Mitral Annular Calcification
Phillip Blankee, MD

9:02 AM - 9:15 AM

Discussion

9:15 AM - 9:23 AM

Is Rheumatic Mitral Valve Repair a Long-term Option?
Kevin D. Accola, MD

9:23 AM - 9:31 AM

Current and Evolving Surgical Management of Mitral Annular calcification
Gorav Ailawadi, MD

9:31 AM - 9:39 AM

Transcatheter Solutions to Mitral Valve Disease Secondary to Annular Calcium
Paul Sorajja, MD

9:39 AM - 9:50 AM

Discussion

9:50 AM - 10:00 AM

47. Histopathological Evaluation Of Chronic Rheumatic Mitral Valve Stenosis:the Association With Clinical Presentation, Pathogenesis And Management At A National Cardiac Institute.
Reuben Kato Mutagaywa¹, Amos Mwakigonja¹, Pilly Chillo¹, Advera Ngaiza¹, Moses Byomuganyizi¹, Lulu Fundikira¹, Gideon Kwesigabo¹, Appolinary Kamuhabwa¹, Maarten Cramer², Steven Chamuleau³.
¹Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania, United Republic of, ²University Medical Centre Utrecht, Utrecht, Netherlands, ³Univeristy Medical Centre Amsterdam, Amsterdam, Netherlands.

Breakout Session 3 - Tricuspid Valve 3

8:30 AM - 10:00 AM

Functional and Atrial Tricuspid Regurgitation
Moderators: Mani Vannan, MD, Molly Szerlip, MD & Yoshi Kaneko, MD

8:30 AM - 8:40 AM

48. Decreased Right Ventricular Free Wall Strain Predicts Increased Mortality Even In The Setting Of Normal Fractional Area Change, Tricuspid Annular Plane Excursion, And Normal Right Ventricular Size In Patients With Greater Than Moderate Tricuspid Regurgita
Vibha Murthy¹, Uswa Khan¹, Elizabeth Wright¹, Shizhen Liu², Pradeep Yadav², Vivek Rajagopal², Amy E. Simone², Vibhav S. Rangarajan³, Peter Flueckiger³, Vinod H. Thourani², Mani A. Vannan².
¹Georgia Institute of Technology and Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, GA, USA, ²Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, GA, USA, ³Piedmont Heart Institute, Atlanta, GA, USA.

8:40 AM - 8:48 AM

Phenotyping TR vs. Classifying TR: Why?
Mani Vannan, MD

8:48 AM - 8:56 AM

Key Clinical Considerations for Durable Relief with Surgery
Robert Smith, MD

8:56 AM - 9:04 AM

Candidates and Outcomes for New Technology in Transcatheter Repair
Firas Zahr, MD

9:04 AM - 9:12 AM

Transcatheter Replacement Therapies that Work
Tarun Chakravarty, MD

9:12 AM - 9:30 AM

Panel Discussion

9:30 AM - 9:40 AM

49. Does Adding A Tricuspid Valve Repair Impact Short And Long Term Outcomes Of Endoscopic Mitral Valve Surgery ?
Mukesh Karuppannan, Abdelbarr Abdelrahman, Palanikumar Saravanan, Andrew Knowles, Argyle Rachel, Grzegorz Laskawski, Joseph Zacharias.
Blackpool Victoria Hospital, Blackpool, United Kingdom.

9:40 AM - 9:50 AM

How-I-Do-It: Surgical Robotic TV repair
T. Sloane Guy, MD

9:50 AM - 10:00 AM

How-I-Do-It: Tri-Clip TV repair
Pradeep Yadav, MD

Breakout Session 4 - Proximal Aorta 2

8:30 AM - 10:00 AM

Proximal Aorta and Valve Disease: Complex Issues in Complex Patients (2 Data Slides and a Case / Video)
Moderators: John Elefteriades, Edward P. Chen, MD, & Elaine E. Tseng, MD

8:30 AM - 8:36 AM

Aortic Disease in Adults with Congenital Heart Disease
Duke E. Cameron, MD

8:36 AM - 8:42 AM

Valve Sparing Root replacement for Dilated Autograft Post Ross
Ismail El-Hamamsy, MD, PhD

8:42 AM - 8:48 AM

Reoperations for Degenerated Stentless Bioprosthetic Root and/or Aortic Homograft
Himanshu Patel, MD

8:48 AM - 8:54 AM

Treating Invasive Aortic Prosthetic Valve Endocarditis
Anar Geirsson, MD

8:54 AM - 9:04 AM

Panel Discussion

9:04 AM - 9:14 AM

50. Long-term Results Of Concomitant Freestyle Aortic Root Replacementand Reconstruction Of The Ascending Aorta
John R. Doty, Rafe C. Connors, William T. Caine, Jean H. Flores, Bruce B. Reid.
Intermountain Medical Center, Murray, UT, USA.

Novel Technology and the Proximal Aorta

9:14 AM - 9:20 AM

PEARS as a Disruptive Technology
John Pepper, MD

9:20 AM - 9:26 AM

ARISE Trial: Site Specific Device for Ascending Aortic Stentgrafting
Eric Roselli, MD

9:26 AM - 9:32 AM

The Endo Bentall Procedure: Reality or Myth
Bradley Leshnower, MD

9:32 AM - 9:50 AM

Panel Discussion

9:50 AM - 10:00 AM

51. Transcatheter Aortic Root Replacement With Coronary Chimney Grafts: Preliminary Results In An In-vitro Model.
Enrico Ferrari, Mira Puthettu, Stefanos Demertzis, Ludwig von Segesser.
Cardiocentro Ticino Institute, LUGANO, Switzerland.

10:00 AM - 10:30 AM

BREAK IN FOYER

PLENARY SESSION V: PROXIMAL AORTA: THE BEST IS YET TO COME

10:30 AM - 12:00 PM

Chairs: Eric E. Roselli, MD, Rania Preventza, MD, & Hector Michelana, MD

10:30 AM - 10:40 AM

What's new on the Aorta in the 2020 ACC/AHA and ESC/EACTS 2021 Guidelines
Duke Cameron, MD

10:40 AM - 10:50 AM

Discussion

10:50 AM - 11:00 AM

Should the threshold for intervention in ascending aorta dilatation be reviewed?
Josh Grimm, MD

11:00 AM - 11:10 AM

From Bench to Bedside: The importance of Basic Science in the Management of Aortic Aneurysm Surgery?
Nimesh D. Desai, MD

11:10 AM - 11:20 AM

Discussion

11:20 AM - 11:30 AM

Current Ross Procedure Outcomes: Can we expand to the Generic Cardiac Surgeon?
Ismail El Hamamsy, MD, PhD

11:30 AM - 11:40 AM

Are there limits for Aortic Valve Repair?
Hans-Joachim Sch�fers, MD

11:40 AM - 11:50 AM

Discussion

11:50 AM - 11:59 AM

Putting it all together and using my Crystal Ball: How will we be Treating the Ascending Aorta in 2030, From Physiology to Patient Preference?
Eric Roselli, MD

11:59 AM - 12:00 PM

Closing Remarks
Marta Sitges, MD & Vinod H. Thourani, MD