The Heart Valve Society

Program and Abstracts | ICTEHV | Posters

WEDNESDAY, 2 MARCH 2022
11:30 AM - 11:35 AM
Opening Remarks
Josh Hutcheson
11:35 PM - 1:00 PM
Session 1 - Engineering Regenerative Heart Valves
Moderators: Josh Hutcheson & Bente de Kort
11:35 PM - 12:00 PM
Keynote Lecture 1
Professor Jane Grande-Allen
12:00 PM - 12:12 PM
I1. Engineering Heart Valve Tissues with Mimetic Biaxial Mechanical Properties using Melt Electrowriting
Bahram Mirani1, Sean Mathew2, Neda Latifi3, Shawn Zahavi4, Brian Amsden2, Craig Simmons1.
1Department of Mechanical & Industrial Engineering, Institute of Biomedical Engineering (BME), University of Toronto - Translational Biology and Engineering Program (TBEP), Ted Rogers Centre for Heart Research, Toronto, ON, Canada, 2Department of Chemical Engineering, Queen's University, Kingston, ON, Canada, 3Department of Mechanical & Industrial Engineering, University of Toronto - Translational Biology and Engineering Program (TBEP), Ted Rogers Centre for Heart Research, Toronto, ON, Canada, 4Translational Biology and Engineering Program (TBEP), University of Toronto - Ted Rogers Centre for Heart Research, Toronto, ON, Canada.
12:12 PM - 12:24 PM
I2. Analyzing The Risk of Calcification in Materials Used for in Situ Heart Valve Tissue Engineering
Dewy C. Valk, van der1, Charlotte M. Hoes1, Yunia M.H. Rasenberg1, Wojtek Szymczyk1, Anat Akiva2, Anthal I.P.M. Smits1, Carlijn V.C. Bouten1.
1Eindhoven University of Technology, Eindhoven, Netherlands, 2Radbout University Medical Center, Nijmegen, Netherlands.
12:24 PM - 12:36 PM
I3. Digital Fabrication Of Highly Tunable Anisotropic Scaffolds For In Situ Heart Valve Tissue Engineering via Melt Electrowriting
Kilian M. A. Mueller, Andreas Unterrainer, Diana M. Rojas-González, Petra Mela.
Technical University of Munich, Garching, Germany.
12:36 PM - 12:48 PM
I4. Non-planar Extrusion Bioprinting For Creating Strain-stiffening Semilunar Valve Leaflets
Benjamin Albert, Coral Wang, Christian Williams, Jonathan Butcher, PhD.
Cornell University, Ithaca, NY, USA.
12:48 PM - 13:00 PM
I5. In Vitro Evaluation of Decellularized Pericardium Based Transcatheter Aortic Valve For Development of Regenerative Heart Valve Prosthesis
Sugat R. Tuladhar1, Sebastian Kaule2, Jan Oldenburg2, Niels Grabow2, Tobias Schilling1, Michael Stiehm2, Axel Haverich1, Klaus-Peter Schmitz2.
1Hannover Medical School, Hannover, Germany, 2Institute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemuende, Germany.
1:00 PM - 1:20 PM
Coffee Break
1:20 PM - 3:00 PM
Session 2 - Understanding TEHV Remodeling
Moderators: Jane Grande-Allen & Dewy van der Valk
1:20 PM - 1:45 PM
Keynote Lecture 2
Professor Katherine Yutzey
1:45 PM - 1:57 PM
I6. Comparison of Tissue Integrity and Morphology of Decellularized Bovine Pericardium with and without Gluteraldehyde Fixation in a Juvenile Sheep Model
Lezelle Botes1, Johan Jordaan2, Jackie Goedhals2, Johannes J. van den Heever2, Pascal M. Dohmen3, Francis E. Smit2.
1Central University of Technology, Bloemfontein, South Africa, 2University of the Free State, Bloemfontein, South Africa, 3University of Rostock, Rostock, Germany.
1:57 PM - 2:09 PM
I7. Multiscale Analysis Of Human Tissue Engineered Matrices For Heart Valve Tissue Engineering Applications
Nikolaos Poulis1, Pascal Breitenstein1, Simon Hofstede2, Maximilian Y. Emmert1, Simon P. Hoerstrup1, Emanuela Fioretta1.
1Institute for Regenerative Medicine, University of Zurich, Zurich, Switzerland, 2Laboratory for Orthopaedic Biomechanics, Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.
2:09 PM - 2:21 PM
I8. Preliminary Assessment Of De-novoCollagen Secretion By VIC-macrophage Co-culture On 3D Engineered Valve Tissues Versus A Porcine Bio-scaffold Valve
Claudia Lorena Ponce Aportela, Oriana Marrone Mantovani, Sharan Ramaswamy.
Biomedical Engineering Department, Florida International University, Miami, FL, USA.
2:21 PM - 2:33 PM
I9. Inflammatory And Regenerative Processes In Bioresorbable Synthetic Pulmonary Valves Up To Two Years In Sheep: The Role Of Hemodynamics
Bente de Kort1, Julia Marzi2, Eva Brauchle2, Arturo Lichauco1, Hannah Bauer3, Aurelie Serrero3, Sylvia Dekker1, Martijn Cox3, Katja Schenke-Layland2, Fred Schoen4, Carlijn Bouten1, Anthal Smits1.
1Tue, Eindhoven, Netherlands, 2Eberhard Karls university, Tübingen, Germany, 3Xeltis BV, Eindhoven, Netherlands, 4Harvard medical school, Boston, MA, USA.
2:33 PM - 2:45 PM
I10. The Potential Of IPSC-derived Macrophages To Assess The Immunocompatibility Of Tissue Engineered Matrices In Vitro
Nikolaos Poulis, Maximilian Y. Emmert, Simon P. Hoerstrup, Emanuela S. Fioretta.
Institute for Regenerative Medicine, University of Zurich, Zurich, Switzerland, Zurich, Switzerland.
2:45 PM - 2:57 PM
I11. Transcatheter Pulmonary Heart Valve with Regenerative True™ Tissue
Zeeshan Syedain.
Vascudyne Inc, St Paul, MN, USA.
2:57 PM - 3:00 PM
Closing Remarks
Josh Hutcheson